Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives (Publications)
18000. 1-Benzyl-1,2-dihydro-2,2,4-trimethylquinolin-6-yl acetate (10a) displayed an IC(50) value of 0.014 muM against these parasites and a selectivity index of 1700. Intraperitoneal administration of 10a
Identification of antischistosomal leads by evaluating bridged 1,2,4,5-tetraoxanes, alphaperoxides, and tricyclic monoperoxides (Publications)
bridged 1,2,4,5-tetraoxane characterized by an adamantane residue showed the highest activity (IC50: 0.3 microM) on adult Schistosoma mansoni. Studies with hemin and heme supplemented medium indicated that
Comparison of rapid methods for detection of <em>Giardia</em> spp. and <em>Cryptosporidium</em> spp. (Oo)cysts using transportable instrumentation in... (Publications)
separation. We were able to detect considerably high oo(cysts) concentrations (ranges: 15-855 and 0-240 oo(cysts)/liter for Giardia and Cryptosporidium, respectively) in 85 to 300 min, with FCM being
Efficacy and safety of artemether against a natural <em>Fasciola hepatica</em> infection in sheep (Publications)
dose, a worm burden reduction of 65.3% was obtained, which was still statistically significant (P < 0.05). The lowest intramuscular dose of artemether investigated (40 mg/kg) yielded no effect on egg counts
Crying babies, tired mothers: What do we know? A systematic review (Publications)
review if they had extractable data on infant crying as well as maternal tiredness in the period of 0-3 months post partum. Of 100 retrieved publications, 10 met these criteria. FINDINGS: evidence from
Meat preparation and colorectal adenomas in a large sigmoidoscopy-based case-control study in California (United States) (Publications)
interval = 1.1-4.3). Adenoma prevalence also increased with frequency of frying red meat (P trend = 0.004). These results are consistent with a carcinogenic effect of HCA
Systematic review of wireless phone use and brain cancer and other head tumors (Publications)
s of the epidemiology studies showed no statistically significant increase in risk (defined as P < 0.05) for adult brain cancer or other head tumors from wireless phone use. Analyses of the in vivo on
Spatial risk prediction and mapping of <em>Schistosoma mansoni</em> infections among schoolchildren living in western Côte d'Ivoire (Publications)
spatial risk modelling and prediction. The infection prevalence of S. mansoni was 38.9%, ranging from 0% to 89.3% among schools. Results showed that age, sex, the richest wealth quintile, elevation and rainfall
Antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (Phaeophyceae) from British and Irish waters (Publications)
tuberculosis, only the B. bifurcata extract was found to have some antitubercular potential (MIC value 64.0 mug/mL). Only three seaweed extracts, i.e. H. siliquosa, B. bifurcata and Cystoseira tamariscifolia
Lagunamide C, a cytotoxic cyclodepsipeptide from the marine cyanobacterium <em>Lyngbya majuscula</em> (Publications)
from 2.1nM to 24.4nM. Compound 1 also displayed significant antimalarial activity with IC(50) value of 0.29muM when tested against Plasmodium falciparum. In addition, lagunamide C exhibited weak anti-swarming
