A point mutation in codon 76 of <em>pfcrt </em>of <em>P. falciparum </em>is positively selected for by chloroquine treatment in Tanzania (Publications)
amounted to a parasitological failure rate of 22.4% using PCR. The mean multiplicity of infection at day 0 was 3.2 (n=71). The allelic frequencies of the mutated pfcrt(76) and pfmdr1(86) were estimated to be
Decentralizing EPI services and prospects for increasing coverage: the case of Tanzania (Publications)
using willingness to pay (WTP) for kerosene (to keep vaccines cool) was low. It was significantly (p < 0.05) associated with whether providers in the nearest health facility properly attended the target population
Airborne particle exposure and extrinsic skin aging (Publications)
aging signs, in particular to pigment spots and less pronounced to wrinkles. An increase in soot (per 0.5 x 10(-5) per m) and particles from traffic (per 475 kg per year and square km) was associated with
High prevalence of mental disorders and comorbidity in the Geneva Gay Men's Health Study (Publications)
phobia, social phobia, alcohol dependence, and drug dependence. RESULTS: Nearly half (43.7%, 95% CI=39.0-48.4) of the sample fulfilled the criteria for at least one of the five DSM-IV disorders: 19.2% had
Severe dengue virus infection in travelers: risk factors and laboratory indicators (Publications)
increased serum alanine and aspartate aminotransferase levels and lower median platelet counts. Two (0.9%) patients fulfilled the World Health Organization (WHO) case definition for dengue hemorrhagic fever
The public health significance and control of schistosomiasis in China - then and now (Publications)
mid 1980s and 2003, the criteria of transmission interruption have been reached in 260 counties (60.0%), transmission control has been achieved in 63 counties (14.5%), but the disease was still endemic
Activities of psilostachyin A and cynaropicrin against <em>Trypanosoma cruzi</em> in vitro and in vivo (Publications)
parasitemia or protect against mortality induced by the Y and Colombiana strains. Psilostachyin A (0.5 to 50 mg/kg/day given once a day) was not effective in the acute model of T. cruzi infection (Y strain)
Activity of praziquantel enantiomers and main metabolites against <em>Schistosoma mansoni</em> (Publications)
shift (i.e. the migration of the worms to the liver) produced by each PZQ enantiomer in mice. IC50s of 0.02, 5.85, 4.08 and 2.42 mug/mL on adult S. mansoni were determined in vitro for R-PZQ, S-PZQ, R-trans
Potential impact of air pollution on multiple sclerosis in Tehran, Iran (Publications)
a clustered pattern in Tehran. A significant difference in exposure to PM10, SO2, NO2, and NOx (p < 0.001) was observed in MS cases compared with controls. Conclusion: This study revealed the potential
Antiprotozoal activity of <em>Buxus sempervirens</em> and activity-guided isolation of <em>O</em>-tigloylcyclovirobuxeine-B as the main constituent... (Publications)
O-tigloylcyclovirobuxeine-B was isolated and evaluated for antiplasmodial activity which yielded an IC50 of 0.455 microg/mL (cytotoxicity against L6 rat cells: IC50 = 9.38 microg/mL). O-tigloylcyclovirobuxeine-B
