Activities of N,N' -diarylurea MMV665852 analogs against <em>Schistosoma mansoni</em> (Publications)
(66%) after a single oral dose of 400 mg/kg to S. mansoni-infected mice. Worm burden reductions of 0-43% were observed for the remaining eight compounds tested. In conclusion, several analogs of N,N'
Chemical constituents from <em>Waltheria indica</em> exert <em>in vitro</em> activity against <em>Trypanosoma brucei</em> and <em>T. cruzi</em> (Publications)
Tulahuen C4. The dichloromethane extract from the roots showed the highest activity against T. cruzi (IC50=0.74mug/mL) as well as a good selectivity index (SI value of 35). Based on these results, this extract
How do clinicians prefer cultural competence training? Findings from the DSM-5 cultural formulation interview field trial (Publications)
age was associated with a preference for behavioral simulations: OR = 1.05 (95 % CI: 1.01-1.10; p = 0.025). CONCLUSIONS: Most clinicians preferred active behavioral simulations in cultural competence training
In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in <em>Plasmodium... (Publications)
thapsigargin with OZ277, artemether or artesunate, against NF54 and K1 strains of P. falciparum ranged from 0.9 to 1.4. CONCLUSION: The interaction of thapsigargin with OZ277, artesunate or artemether was additive
Measurement of overall insecticidal effects in experimental hut trials (Publications)
alternative definition for the measurement of the overall insecticidal effect has the desirable range of 0 to 1 (100%), provided mortality among non-repelled mosquitoes in the treated hut is less than the c
Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications (Publications)
nets (ITNs); 68% in Ifakara and zero in Manhica. In Ifakara, IPTi was associated with a 53% (95% CI 14.0; 74.1) reduction in the risk of clinical malaria between the second and the third dose; during the same
Diagnosis, treatment and risk factors of <em>Strongyloides stercoralis</em> in schoolchildren in Cambodia (Publications)
infected with S. stercoralis. The sensitivity of KAP culture and Baermann technique was 88.4% and 75.0%, respectively and their negative predictive values were 96.4% and 92.5%, respectively. The cumulative
Adenosine kinase of <em>T. b. Rhodesiense</em> identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical... (Publications)
razol-3-yl]morpholine (compound 1) exhibits specific antitrypanosomal activity with an IC(50) of 1.0 microM on Trypanosoma brucei rhodesiense (T. b. rhodesiense), the causative agent of the acute form
An in-depth analysis of a piece of shit: distribution of <em>Schistosoma mansoni</em> and hookworm eggs in human stool (Publications)
pattern of S. mansoni and hookworm eggs in fecal samples. Homogenization decreased S. mansoni FECs (p = 0.026), while no effect was observed for hookworm and other soil-transmitted helminths. Hookworm FECs
<em>Strongyloides ratti</em>: in vitro and in vivo activity of tribendimidine (Publications)
n of the larval and adult worm burden. For comparison, we also administered ivermectin at a single 0.5 mg/kg oral dose to rats infected with adult S. ratti and found a 90% reduction of larvae and a 100%
