Safety and differential antibody and T-cell responses to <em>Plasmodium falciparum</em> sporozoite vaccine by age in Tanzanian adults, adolescents,... (Publications)
vaccinees and controls or between dosage regimens. Because all age groups received three doses of 9.0 x 10(5) PfSPZ of PfSPZ Vaccine, immune responses were compared at this dosage. Median antibody responses
Evaluation of the novel substrate RUG™ for the detection of<em> Escherichia coli</em> in water from temperate (Zurich, Switzerland) and tropical... (Publications)
(C-18), m-TEC and m-ColiBlue24®. In temperate waters, AT-RUG was found to be as sensitive as m-TEC (97.0%) and C-18 (98.5%) and showed strong agreement with the reference methods. The false-positive rate for
Physiologically based pharmacokinetic modelling to identify pharmacokinetic parameters driving drug exposure changes in the elderly (Publications)
1.25-fold (70%), 1.5-fold (86%) and 2-fold (100%) of clinical data. AUC increased progressively by 0.9% per year throughout adulthood from the age of 20 years, which was explained by decreased clearance
Prevalence and adverse obstetric outcomes of female genital mutilation among women in rural northern Ghana (Publications)
than 35 years compared with those without FGM (7.6%). FGM declined progressively from 28.4% in 2003 to 0.6% in 2013. Mothers with FGM were nearly twice as likely to have caesarean delivery (adjusted odds ratios
Atopy modifies the association between inhaled corticosteroid use and lung function decline in patients with asthma (Publications)
whether the association between ICS use and FEV1 decline was modified by allergic sensitization (IgE > 0.35 kU/L for any of house-dust mite, timothy grass, cat, or Cladosporium). RESULTS: FEV1 decline was
High prevalence of <em>Schistosoma haematobium</em> x <em>Schistosoma bovis</em> hybrids in schoolchildren in Côte d'Ivoire (Publications)
haplotypes. Of 40 ITS 2 sequences analysed, 31 (77.5%) were assigned to pure S. haematobium, four (10.0%) to pure S. bovis and five (12.5%) to S. haematobium-bovis hybrids. Our findings suggest that S. h
Variability and predictors of weekly pesticide exposure in applicators from organic, sustainable and conventional smallholder farms in Costa Rica (Publications)
average weekly exposures within and between workers, respectively; intraclass correlation coefficient=0.4). Applicators working on conventional and sustainable farms had exposure scores twofold and 1.5-fold
Clinical study on the melarsoprol-related encephalopathic syndrome: risk factors and HLA association (Publications)
ted mortality. Haplotype C*14/B*15 was associated with an elevated risk for ES (OR: 6.64; p-value: 0.008). Haplotypes A*23/C*14, A*23/B*15 and DR*07/B*58 also showed a weaker association with ES. This
TNFA-308 in Two International Population-Based Cohorts Shows Increased Risk for Asthma (Publications)
ratio for the A allele=1.3, 95%CI 1.1-1.5) and with bronchial hyper-responsiveness (OR=1.2, 95%CI 1.0-1.3). No consistent association was found for atopy. The LTA+252 polymorphism was not associated with
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of... (Publications)
[95% UI 111.2 million to 137.0 million]), high systolic blood pressure (122.2 million DALYs [110.3 million to 133.3 million], and low birthweight and short gestation (83.0 million DALYs [78.3 million to
