A tool box for operational mosquito larval control: preliminary results and early lessons from the Urban Malaria Control Programme in Dar es Salaam,... (Publications)
transmission by the primary malaria vector, Anopheles gambiae s.l., by 31% (95% C.I. = 21.6-37.6%; p = 0.04). CONCLUSION: This novel management, monitoring and evaluation system for implementing routine l
Estimating the burden of malaria in Senegal: Bayesian zero-inflated binomial geostatistical modeling of the MIS 2008 data (Publications)
quintiles. Infection odds appear to be increasing with age. The population-adjusted prevalence ranges from 0.12% in Thille-Boubacar to 13.1% in Dabo. Tambacounda has the highest population-adjusted predicted
Comparative analysis of <em>Mycobacterium tuberculosis</em> <em>pe </em>and <em>ppe</em> genes reveals high sequence variation and an apparent absence... (Publications)
M. tuberculosis phylogenetic tree. We show that nsSNP's in pe (excluding pgrs) and ppe genes are 3.0 and 3.3 times higher than in non-pe/ppe genes respectively and that numerous other mutation types are
Safety of falciparum malaria diagnostic strategy based on rapid diagnostic tests in returning travellers and migrants: a retrospective study (Publications)
were recruited. 2028 had both initial RDT and blood smear (BS) result negative. Among those, 2/2028 (0.1%) developed uncomplicated malaria with both RDT and BS positive on day 1 and day 6 respectively. Among
Identification of compounds with anti-proliferative activity against <em>Trypanosoma brucei brucei</em> strain 427 by a whole cell viability based HTS... (Publications)
of eight compounds for further biological analysis. These compounds had IC(50) values ranging from 0.22 µM to 4 µM with associated selectivity indices ranging from 19 to greater than 345. Further testing
Activity of oxantel pamoate monotherapy and combination chemotherapy against <em>Trichuris muris</em> and hookworms: revival of an old drug (Publications)
antagonistic effects in vivo (CI = 1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI = 0.15) was observed when oxantel pamoate-mebendazole was administered to T. muris-infected mice. Oxantel
Development of an in vitro drug sensitivity assay for <em>Trichuris muris</em> first-stage larvae (Publications)
effect data in vitro. IC50 values for nitazoxanide, levamisole and oxantel pamoate were 4.43, 1.75 and 0.05 mug/mL, respectively. Mebendazole and ivermectin failed to show any trichuricidal effect on L1. No
Ownership and usage of mosquito nets after four years of large-scale free distribution in Papua New Guinea (Publications)
7%. Among children under five years, usage of LLINs and of nets in general increased from 8.2% to 67.0% and from 44.6% to 76.1%, respectively (all p
Transmission of malaria in relation to distribution and coverage of long-lasting insecticidal nets in central Côte d'Ivoire (Publications)
ib/h/y, while in the intervention villages, the EIR decreased significantly from 514.6 ib/h/y to 62.0 ib/h/y (Bozi) and from 83.9 ib/h/y to 25.5 ib/h/y (Yoho). The risk of an infectious bite over the three-year
Strategies for detection of <em>Plasmodium species</em> gametocytes (Publications)
falciparum positivity of 24.1%; of these 40.8% carried gametocytes. P. vivax positivity was 38.4%, with 38.0% of these carrying gametocytes. Sensitivity of DNA-based parasite detection was substantially lower
