Boosting effect of IL-7 in interferon gamma release assays to diagnose <em>Mycobacterium tuberculosis</em> infection (Publications)
IFN-gamma in individuals with active TB from 4.2IU/ml (IQR 1.4-6.9IU/ml) to 5.1IU/ml (IQR 1.5-8.1IU/ml, p = 0.0057), and we found an indication of a lower release of both IFN-gamma and IP-10 in participants with
Long-term exposure to ambient air pollution and lower respiratory tract infection in adults: Danish nationwide evidence (Publications)
hazard ratios (95% confidence interval) of 1.08 (1.07, 1.09) per 10 μg/m3 for NO2, 1.07 (1.06, 1.08) per 0.5 10-5 m-1 for BC, and 1.04 (1.03, 1.04) per 2 μg/m3 for PM2.5. We detected similar associations with
Assessment of health status and creation of a registry of potential research participants aged 1.5 to 50 years on Bioko Island, Equatorial Guinea (Publications)
into the registry. Among those screened, 13.6% had Plasmodium, 1.8% had Loa loa, 4.8% had hepatitis B, 0.5% had hepatitis C, and 2.1% had HIV. Adults were twice as likely to have clinically relevant medical
Auto-induced uplink 4G and 5G RF-EMF exposure assessment using a network monitoring application in different microenvironments across seven European... (Publications)
highest average transmit powers per microenvironment (median 20.6 dBm). Transmit powers in villages were 0.6-2.1 dB higher than in big cities. The study suggested that base station density is a key predictor
Human granulocytotropic anaplasmosis: a systematic review and analysis of the literature (Publications)
organ failure 7.5%, ARDS 6.3%, a.o.), sequelae are rare (2.1% of the cases) and lethality is low (3.0% of the cases). Treatment with doxycycline shows a rapid response, with the fever subsiding in the majority
Human granulocytotropic anaplasmosis - a systematic review and analysis of the literature (Publications)
organ failure 7.5%, ARDS 6.3%, a.o.), sequelae are rare (2.1% of the cases) and lethality is low (3.0% of the cases). Treatment with doxycycline shows a rapid response, with the fever subsiding in the majority
Human African trypanosomiasis (Publications)
cases. The treatment-related mortality rate consequently dropped from 5% with melarsoprol to around 0.5%. A single-dose oral treatment, acoziborole, has completed Phase III trials and may further revolutionize
Computer-aided detection thresholds for digital chest radiography interpretation in tuberculosis diagnostic algorithms (Publications)
status determined; 142 had tuberculosis. Prevalence estimates varied between methodological approaches (0.83-2.72%). Using multiple imputation to estimate tuberculosis status for those eligible but not tested
Urinary pesticide mixture patterns and exposure determinants in the adult population from the Netherlands and Switzerland: application of a suspect... (Publications)
Within-individual correlations in repeated samples (summer/winter) from the Netherlands were low (≤0.3), and no seasonal differences in average exposures were observed in Switzerland. CONCLUSION: High
Development and evaluation of PlasmoPod: a cartridge-based nucleic acid amplification test for rapid malaria diagnosis and surveillance (Publications)
than 30 minutes. Our analytical performance evaluation indicates that a limit-of-detection as low as 0.02 parasites/μL can be achieved and no cross-reactivity with other pathogens common in malaria endemic