Identification of compounds with anti-proliferative activity against <em>Trypanosoma brucei brucei</em> strain 427 by a whole cell viability based HTS... (Publications)
of eight compounds for further biological analysis. These compounds had IC(50) values ranging from 0.22 µM to 4 µM with associated selectivity indices ranging from 19 to greater than 345. Further testing
Activity of oxantel pamoate monotherapy and combination chemotherapy against <em>Trichuris muris</em> and hookworms: revival of an old drug (Publications)
antagonistic effects in vivo (CI = 1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI = 0.15) was observed when oxantel pamoate-mebendazole was administered to T. muris-infected mice. Oxantel
Development of an in vitro drug sensitivity assay for <em>Trichuris muris</em> first-stage larvae (Publications)
effect data in vitro. IC50 values for nitazoxanide, levamisole and oxantel pamoate were 4.43, 1.75 and 0.05 mug/mL, respectively. Mebendazole and ivermectin failed to show any trichuricidal effect on L1. No
Ownership and usage of mosquito nets after four years of large-scale free distribution in Papua New Guinea (Publications)
7%. Among children under five years, usage of LLINs and of nets in general increased from 8.2% to 67.0% and from 44.6% to 76.1%, respectively (all p
Transmission of malaria in relation to distribution and coverage of long-lasting insecticidal nets in central Côte d'Ivoire (Publications)
ib/h/y, while in the intervention villages, the EIR decreased significantly from 514.6 ib/h/y to 62.0 ib/h/y (Bozi) and from 83.9 ib/h/y to 25.5 ib/h/y (Yoho). The risk of an infectious bite over the three-year
Strategies for detection of <em>Plasmodium species</em> gametocytes (Publications)
falciparum positivity of 24.1%; of these 40.8% carried gametocytes. P. vivax positivity was 38.4%, with 38.0% of these carrying gametocytes. Sensitivity of DNA-based parasite detection was substantially lower
Investigating mosquito net durability for malaria control in Tanzania - attrition, bioefficacy, chemistry, degradation and insecticide resistance... (Publications)
Those households will receive one of three leading LLIN products at random (Olyset(R), PermaNet(R)2.0 or Netprotect(R)) and will be followed up for three years in a prospective study to compare their p
Evaluation of farm-level parameters derived from animal movements for use in risk-based surveillance programmes of cattle in Switzerland (Publications)
parameters. Different cut offs; 50, 90, 95 and 99 %, were explored. The final scores ranged between 0 and 5. Validation of the scores against results from the BVD surveillance programme 2013 gave promising
Carotid artery intima-media thickness in college students: race/ethnicity matters (Publications)
Race/ethnicity was also strongly associated with CIMT. African Americans had 17.3mum greater CIMT (95%CI -0.3, 34.8) compared to non Hispanic Whites, whereas Asians and Hispanic Whites had 14.3 (95%CI -24.3,
Acute effects of ambient ozone on respiratory function of Swiss schoolchildren after a 10-minute heavy exercise (Publications)
adjusted regression coefficient for delta-peak flow on ozone was -2.28 mL/s/micrograms/m3 (95% CI, -0.57 -3.99). It is noteworthy that the observed relationships occurred at ozone concentrations below 160
