Genomic diversity among drug sensitive and multidrug resistant isolates of <em>Mycobacterium tuberculosis</em> with identical DNA fingerprints (Publications)
pattern and the same allele at 23 out of 24 MIRU-VNTR loci. We generated 23.9 million (K-1) and 33.0 million (K-2) paired 50 bp purity filtered reads corresponding to a mean coverage of 483.5 fold and
Recent HIV-1 infection: identification of individuals with high viral load setpoint in a voluntary counselling and testing centre in rural Mozambique (Publications)
47) as compared to the median of 4.15 log(10) copies/ml (IQR 3.37-4.43) for the other patients (p = 0.0001). CONCLUSION: The low proportion of recent HIV-infections among HIV-seropositive VCT clients suggests
Sterilising effects of pyriproxyfen on <em>Anopheles arabiensis</em> and its potential use in malaria control (Publications)
retention of eggs (97% of eggs retained, i.e. produced in the ovaries but not laid, in regimen B, p = 0.0004). Some of these retained eggs were deformed in shape. PPF exposure on mosquito survival in the
Ecological model to predict potential habitats of <em>Oncomelania hupensis</em>, the intermediate host of <em>Schistosoma japonicum</em> in the... (Publications)
potential O. hupensis habitats prediction comprised the following environmental factors, namely: NDVI (> /= 0.446), LST (> /= 22.70 degrees C), elevation (
Long-term air pollution and traffic noise exposures and mild cognitive impairment in older adults: a cross-sectional analysis of the Heinz Nixdorf... (Publications)
y). In two-exposure models, AP and noise associations were attenuated (i.g., for aMCI: PM2.5 1.13 (0.98, 1.30) and LDEN 1.46 (1.11, 1.92)). CONCLUSIONS: Long-term exposures to air pollution and traffic
Excess mortality during the warm summer of 2015 in Switzerland (Publications)
minimum night-time temperature reached extreme values (+32 and +20 degrees C, respectively), with 31.0% extra deaths for periods of three days or more. CONCLUSIONS: Heat during summer 2015 was associated
Malaria vectors and their blood-meal sources in an area of high bed net ownership in the western Kenya highlands (Publications)
bovines. Single blood-meal sources by An. gambiae s.s. from humans were 26.5 %, 8.2 % from bovines and 2.0 % from goats. Mixed blood-meal sources by An. gambiae s.s. identified included: 24.5 % human/goat, 10
Estimating the burden of scrub typhus: a systematic review (Publications)
India and northern Thailand, respectively. Mortality reports vary widely around a median mortality of 6.0% for untreated and 1.4% for treated scrub typhus. Limited evidence suggests high mortality in complicated
Impact of malaria interventions on child mortality in endemic African settings: comparison and alignment between LiST and Spectrum-Malaria model (Publications)
among other interventions, on malaria infection prevalence, case incidence and mortality in children 0-4 years, 5-14 years of age and adults. Spectrum-Malaria uses statistical models fitted to simulations
Screening of the 'Open Scaffolds' collection from<em> Compounds Australia</em> identifies a new chemical entity with anthelmintic activities against... (Publications)
"coiled" xL3 phenotype (IC50 = 3.46-5.93 muM), inhibited motility of fourth-stage larvae (L4s; IC50 = 0.31-12.5 muM) and caused considerable cuticular damage to L4s in vitro. When tested on other parasitic