Guide posts for investment in primary health care and projected resource needs in 67 low-income and middle-income countries: a modelling study (Publications)
incremental PHC costs would be about 3.3% of projected gross domestic product (GDP; median 1.7%, range 0.1-20.2). In a business-as-usual financing scenario, 25 of 67 countries will have funding gaps in 2030
Rabies (Publications)
biologically feasible due to efficacious, safe and cheap vaccines and the low basic reproductive ratio (R0) of the disease. It is well known that mass dog vaccination is a cost-effective, sustainable measure
Global, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019 (Publications)
children younger than 5 years, with 112 000 deaths (87 400-145 000) and 1·28 million incident cases (0·947-1·71) in 2019. Age-standardised mortality rates decreased from 7·5 (6·6-8·4) per 100 000 population
Specialized active leprosy search strategies in an endemic area of the Brazilian Amazon identifies a hypermutated <em>Mycobacterium leprae</em> strain... (Publications)
individuals, 22 in treated cases, 24 in newly diagnosed leprosy cases, and 78 in HHC. We detected 29.0% (36/124) positivity overall in this sample set. The positivity in treated cases was 31.8% (7/22), while
Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019 (Publications)
DALYs per 100 000 also remained largely unchanged in high-SDI countries (555 in 2010 vs 554 in 2019; 0.2% reduction). The number and rate of adolescent deaths and DALYs owing to environmental heat and cold
Efficacy and safety of ascending doses of moxidectin against<em> Strongyloides stercoralis</em> infections in adults: a randomised, parallel-group,... (Publications)
northern Laos. Eligible adults (aged 18-65 years) with S stercoralis infection intensities of at least 0.4 larvae per g of stool in at least two stool samples were randomly assigned (1:1:1:1:1:1:1) by use
Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part II. An approach to retrospective... (Publications)
reliability of estimated lifetime exposure to ozone was high, with intraclass correlations greater than 0.90 for all approaches evaluated. Multiple, linear regression analyses showed a consistently negative
A randomized placebo-controlled phase a malaria vaccine trial of two virosome-formulated synthetic peptides in healthy adult volunteers (Publications)
AMA-1 and the CSP virosomal vaccine, respectively) or unmodified virosomes were injected i. m. on days 0, 60 and 180. In terms of safety, no serious or severe adverse events (AEs) related to the vaccine were
Childhood incident asthma and traffic-related air pollution at home and school (Publications)
traffic-related pollution at school and home, whereas the estimate for NO2 was attenuated (HR 1.37; 95% CI, 0.69-2.71). Conclusions: Traffic-related pollution exposure at school and homes may both contribute to
Urine-Xpert Ultra for the diagnosis of tuberculosis in people living with HIV: a prospective, multicentre, diagnostic accuracy study (Publications)
t Ultra and AlereLAM were 32·7% (95% CI 27·2-38·7) and 30·7% (25·4-36·6) and specificities were 98·0% (97·1-98·6) and 90·4% (88·7-91·8), respectively. Against CRS as reference, sensitivities of Urine-Xpert
