Sesquiterpene lactones from <em>Vernonia cinerascens </em>sch. bip. and their <em>in vitro</em> antitrypanosomal activity (Publications)
new germacrolide type sesquiterpene lactone vernocinerascolide (8) from the dichloromethane extract of V. cinerascens leaves. Compounds 3-8 were characterized by extensive analysis of their 1D and 2D NMR
Efficacy of drugs against clonorchiasis and opisthorchiasis: a systematic review and network meta-analysis (Publications)
regimens, including 20 mg/kg three times a day for 3 days (97.6% [74.7-99.8]), 14 mg/kg three times a day for 5 days (93.9% [44.8-99.7]), and 20 mg/kg twice a day for 3 days (91.0% [50.9-99.0]). In O viverrini [...] [64.9-98.6]). The single dose of 400 mg tribendimidine showed a high predicted cure rate of 89.8% (77.5-95.8). A low quality of evidence was demonstrated in most studies, especially those published before [...] mg/kg and 25 mg/kg of praziquantel given in a single day showed the...
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of... (Publications)
9-11.6) decline in deaths and a 10.8% (8.3-13.1) decrease in DALYs at the global level, while population ageing accounts for 14.9% (12.7-17.5) of deaths and 6.2% (3.9-8.7) of DALYs, and population growth [...] [80.9 million to 98.2 million]), high body-mass index (64.8 million DALYs [44.4 million to 87.6 million]), and high fasting plasma glucose (63.8 million DALYs [53.2 million to 76.3 million]). In 2016 in
Efficacy of drugs against clonorchiasis and opisthorchiasis: a systematic review and network meta-analysis (Publications)
regimens, including 20 mg/kg three times a day for 3 days (97.6% [74.7-99.8]), 14 mg/kg three times a day for 5 days (93.9% [44.8-99.7]), and 20 mg/kg twice a day for 3 days (91.0% [50.9-99.0]). In O viverrini [...] [64.9-98.6]). The single dose of 400 mg tribendimidine showed a high predicted cure rate of 89.8% (77.5-95.8). A low quality of evidence was demonstrated in most studies, especially those published before [...] mg/kg and 25 mg/kg of praziquantel given in a single day showed the...
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of... (Publications)
9-11.6) decline in deaths and a 10.8% (8.3-13.1) decrease in DALYs at the global level, while population ageing accounts for 14.9% (12.7-17.5) of deaths and 6.2% (3.9-8.7) of DALYs, and population growth [...] [80.9 million to 98.2 million]), high body-mass index (64.8 million DALYs [44.4 million to 87.6 million]), and high fasting plasma glucose (63.8 million DALYs [53.2 million to 76.3 million]). In 2016 in
The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of <em>pfmdr1... (Publications)
(95% CI 10.7-15.7) for AL and 15.2 days (95% CI 12.8-18.4) for AS-AQ overall. However, the duration varied significantly between trial sites, from 8.7-18.6 days for AL and 10.2-18.7 days for AS-AQ. Significant [...] benefit to patients in higher transmission areas. METHODS: We analyzed individual patient data from 8 clinical trials of AL versus AS-AQ in 12 sites in Africa (n = 4214 individuals). The time to PCR-confirmed
Effect of ambient air pollution on hospital admission for respiratory diseases in Hanoi children during 2007-2019 (Publications)
ion of PM(10), PM(2.5), PM(1), SO(2), NO(2), O(3) 8-h maximum and 1000 μg/m(3) increase in CO concentration was associated with 0.6%, 1.2%, 1.4%, 0.8%, 1.6%, 0.3%, and 1.7% increase in odd of admission [...] particulate matter (e.g. PM(1), PM(2.5), PM(10)), Sulfur Dioxide (SO(2)), Nitrogen Dioxide (NO(2)), 8-h maximum Ozone and per 1000 μg/m(3) increase in daily mean of Carbon Monoxide (CO). We also calculated
Moderate-to-vigorous physical activity is associated with cardiorespiratory fitness among primary schoolchildren living in Côte d'Ivoire, South... (Publications)
were used, including 499 children from CI (Taabo, 49% girls, M = 8.0 +/- 1.6 years), 1,074 children from ZA (Gqeberha, 49% girls, M = 8.3 +/- 1.4 years), and 593 children from TZ (Ifakara, 51% girls, M [...] (boys: 91.7%, girls: 87.4%), whereas this rate was 76.9% in ZA (boys: 91.0%, girls: 62.4%), and 93.8% in TZ (boys: 95.5%, girls: 92.0%). Children from TZ had the highest CRF and MVPA levels, followed by
Relation between organophosphate pesticide metabolite concentrations with pesticide exposures, socio-economic factors and lifestyles: a... (Publications)
area, Hex River Valley (median = 61.8 ng/ml; beta = -52.1; 95% CI: -97.9, -6.3 ng/ml) and the wheat farming area, Piketberg (median = 72.4 ng/ml; beta = -54.2; 95% CI: 98.8, -9.7 ng/ml) lower than those in [...] 14 years had lower DAP urine concentrations (median = 39.9 ng/ml; beta = -68.1 ng/ml; 95% CI: -136.8, 0.6) than children aged 9 years and younger (median = 107.0 ng/ml). DAP concentrations also varied
Radiofrequency electromagnetic fields from mobile communication: description of modeled dose in brain regions and the body in European children and... (Publications)
children (median 81.8 mJ/kg/day). Children spent more time using tablets or laptops compared to adolescents, resulting in higher RF doses in the whole-body (median whole-body dose of 81.8 mJ/kg/day) compared [...] midbrain, occipital lobe, parietal lobe, temporal lobes) and the whole-body in 8358 children (ages 8-12) and adolescents (ages 14-18) from the Netherlands, Spain, and Switzerland during 2012-2016. The
