8-O-methyldioncophyllinol B and revised structures of other 7,6'- coupled naphthylisoquinoline alkaloids from <em>Triphyophyllum peltatum... (Publications)
The isolation and structural elucidation of a new naphthylisoquinoline alkaloid, 8-O-methyldioncophyllinol B, from Triphyophyllum peltatum (Hutch. et Dalz.) Airy Shaw (Dioncophyllaceae) is described, together [...] structures of other 'B-type' compounds previously misidentified as dioncophylline D, dioncophyllinol D, and 8-O- methyldioncophylline D. All of the presently described structures are 7,6'-coupled and thus have [...] quinoline alkaloids. This is in contrast to the initially...
Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described... (Publications)
unprecedented 5,3'-coupling type between the naphthalene and isoquinoline portions, while 6 and 7 are 5,8'-coupled. The structures of the compounds were determined by spectroscopic, chemical, and chiroptical
Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers) (Publications)
Six tetraoxanes had 50% inhibitory concentrations in the range of 10 to 100 ng/ml against Plasmodium falciparum, whereas the corresponding hexaoxonanes had minimal antimalarial activity. The lack of i
Cytokeratin 8 is a suitable epidermal marker during zebrafish development (Publications)
We have cloned and characterized the zebrafish (Danio rerio) homologous cytokeratin 8 (zf-K8) cDNA. This cytokeratin belongs to the gene family of intermediate filaments and it is a component of the c [...] intestinal progenitors. During later embryonic stage zf-K8 mRNA is strongly expressed in the developing pectoral fin. In adult zebrafish, the zf-K8 gene is not only expressed in simple epithelia such as [...] expression analysis during embryonic development and at adult stages presented here...
Zebrafish keratin 8 is expressed at high levels in the epidermis of regenerating caudal fin (Publications)
zebrafish (Danio rerio) homologous cytokeratin 8 cDNA (zfk8) which was described as an epidermal marker during zebrafish development. It has been found that the zfk8 gene is normally expressed in simple epithelia [...] and are mainly expressed in epithelial cells. In several vertebrates it has been shown that keratin 8 is expressed in simple epithelial tissues, some non-epithelial tissue and in hyper-proliferative tissues [...] mature zebrafish. Using whole-mount in situ hybridisation, we show...
Summary of the animal homologue section of HLDA8 (Publications)
Development of reagents against leukocyte differentiation antigens in veterinary immunology is slower compared to humans and mice. Cross-reactivity studies with monoclonal antibodies (mAb) generated a
