Distribution and treatment needs of soil-transmitted helminthiasis in Bangladesh: a Bayesian geostatistical analysis of 2017-2020 national survey data (Publications)
BACKGROUND: In Bangladesh, preventive chemotherapy targeting soil-transmitted helminth (STH) infections in school-age children has been implemented since 2008. To evaluate the success of this strategy [...] conducted between 2017 and 2020 in 10 out of 64 districts. We estimate the geographic distribution of STH infections by species at high spatial resolution, identify risk factors, and estimate treatment needs [...] population subgroups. METHODOLOGY: Bayesian geostatistical models were fitted...
Bayesian geostatistical model-based estimates of soil-transmitted helminth infection in Nigeria, including annual deworming requirements (Publications)
BACKGROUND: The acceleration of the control of soil-transmitted helminth (STH) infections in Nigeria, emphasizing preventive chemotherapy, has become imperative in light of the global fight against neglected [...] Predictive risk maps are an important tool to guide and support control activities. METHODOLOGY: STH infection prevalence data were obtained from surveys carried out in 2011 using standard protocols. [...] covariates and variable selection procedures were utilized to predict the...
Bayesian geostatistical model-based estimates of soil-transmitted helminth infection in Nigeria, including annual deworming requirements (Publications)
BACKGROUND: The acceleration of the control of soil-transmitted helminth (STH) infections in Nigeria, emphasizing preventive chemotherapy, has become imperative in light of the global fight against neglected [...] Predictive risk maps are an important tool to guide and support control activities. METHODOLOGY: STH infection prevalence data were obtained from surveys carried out in 2011 using standard protocols. [...] covariates and variable selection procedures were utilized to predict the...
Cost analysis for “The Magic Glasses Philippines” health education package to prevent intestinal worm infections among Filipino schoolchildren (Publications)
Glasses Philippines (MGP)” health education package in reducing STH infections among schoolchildren in intervention schools with ≤15% STH baseline prevalence in Laguna province, the Philippines. To inform [...] Background: Soil-transmitted helminth (STH) infections are a significant public health problem affecting over 900 million people globally. Health education has been shown to complement mass drug administration [...] the actual RCT and the total costs for regional and national scale-up in...
Cost analysis for “The Magic Glasses Philippines” health education package to prevent intestinal worm infections among Filipino schoolchildren (Publications)
Glasses Philippines (MGP)” health education package in reducing STH infections among schoolchildren in intervention schools with ≤15% STH baseline prevalence in Laguna province, the Philippines. To inform [...] Background: Soil-transmitted helminth (STH) infections are a significant public health problem affecting over 900 million people globally. Health education has been shown to complement mass drug administration [...] the actual RCT and the total costs for regional and national scale-up in...
efficacy and reduce the risk of STH infections in the most vulnerable populations,” said Keiser. “In addition, DRUGSBUGS will investigate novel drug screening tools for STH to fill the depleted drug discovery [...] Soil-transmitted helminth (STH) infections are among the most common infections worldwide and affect an estimated 1.5 billion people, particularly in low- and middle-income countries. Intestinal worms [...] Keiser and her research team will investigate the effects of gut communities...
Therapeutic efficacy of albendazole against soil-transmitted helminthiasis in children measured by five diagnostic methods (Publications)
Preventive chemotherapy (PC) with benzimidazole drugs is the backbone of soil-transmitted helminth (STH) control programs. Over the past decade, drug coverage has increased and with it, the possibility of [...] to the recommended single Kato-Katz. METHODS: An ALB efficacy trial was performed in 3 different STH-endemic countries (Ethiopia, Lao PDR and Tanzania), each with a different PC-history. During these [...] diagnostic methods could provide reduction rates that were equivalent to a single...
Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted... (Publications)
and infection intensities, the use of the correct diagnostic method is of utmost importance. The STH community has recently published for each phase of a deworming program the minimal criteria that a [...] Mini-FLOTAC and FECPAKG2) and one DNA-based method (qPCR) for the detection and quantification of STH infections in three drug efficacy trials in Ethiopia, Lao PDR, and Tanzania. Furthermore, we evaluated [...] TPPs. PRINCIPAL FINDINGS: All diagnostic methods showed a clinical sensitivity of...
Therapeutic efficacy of albendazole against soil-transmitted helminthiasis in children measured by five diagnostic methods (Publications)
Preventive chemotherapy (PC) with benzimidazole drugs is the backbone of soil-transmitted helminth (STH) control programs. Over the past decade, drug coverage has increased and with it, the possibility of [...] to the recommended single Kato-Katz. METHODS: An ALB efficacy trial was performed in 3 different STH-endemic countries (Ethiopia, Lao PDR and Tanzania), each with a different PC-history. During these [...] diagnostic methods could provide reduction rates that were equivalent to a single...
Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted... (Publications)
and infection intensities, the use of the correct diagnostic method is of utmost importance. The STH community has recently published for each phase of a deworming program the minimal criteria that a [...] Mini-FLOTAC and FECPAKG2) and one DNA-based method (qPCR) for the detection and quantification of STH infections in three drug efficacy trials in Ethiopia, Lao PDR, and Tanzania. Furthermore, we evaluated [...] TPPs. PRINCIPAL FINDINGS: All diagnostic methods showed a clinical sensitivity of...
