Searched for "8".

1. Ealamines A-H, a series of naphthylisoquinolines with the rare 7,8'-coupling site, from the Congolese liana <em>Ancistrocladus ealaensis</em>,... (Publications)

   Ealamines A-H, a series of naphthylisoquinolines with the rare 7,8'-coupling site, from the Congolese liana <em>Ancistrocladus ealaensis</em>, targeting pancreatic cancer cells

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   are the first 7,8'-linked "hybrid-type" naphthylisoquinoline alkaloids, i.e., 3R-configured and 6-oxygenated in the tetrahydroisoquinoline part. The discovery of such a broad series of 7,8'-coupled naph [...] leaves of the Central African liana Ancistrocladus ealaensis (Ancistrocladaceae), a series of ten 7,8'-coupled naphthylisoquinoline alkaloids were isolated, comprising eight new compounds, named ealamines

2. Bedaquiline, moxifloxacin, pretomanid, and pyrazinamide during the first 8 weeks of treatment of patients with drug-susceptible or drug-resistant... (Publications)

   Bedaquiline, moxifloxacin, pretomanid, and pyrazinamide during the first 8 weeks of treatment of patients with drug-susceptible or drug-resistant pulmonary tuberculosis: a multicentre, open-label, partially randomised, phase 2b trial

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3. A triple win awaits (Page)

   A triple win awaits

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   hardly any travel was undertaken at Swiss TPH. Globally, greenhouse gas emissions have fallen by around 8% in 2020, according to the Lancet Countdown Report . In 2020, hardly any travel was undertaken at Swiss [...] food security, migration and much more. "Globally, greenhouse gas emissions have fallen by around 8% in 2020. The world has achieved what is needed for the 1.5 degree target, not with climate policy, [...] countries were less than 300kg per person in 2018. In Switzerland, emissions...

4. Winter Symposium 2017 (Page)

   Winter Symposium 2017

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   Helminth Infection - from Transmission to Control Swiss TPH Winter Symposium - 7-8 December 2017 - Parterre Rialto, Basel, Switzerland The Swiss TPH Winter Symposium 2017 invites medical parisitologists [...] Accelerating Progress on NTDs – New Frontiers, Yael Velleman, WaterAid, UK 17:00 End of Day 1 Friday, 8 December 2017 Session 5 – Helminth Infection: Pain and Gain Chairs: O. Fedorova, Siberian State Medical

5. Winter Symposium 2016 (Page)

   Winter Symposium 2016

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   Building on Success - Malaria Control and Elimination Swiss TPH Winter Symposium - 8-9 December 2016 - Congress Center Basel, Switzerland The Swiss TPH Winter Symposium 2016 invites medical and health [...] ce and Health Systems Country Issues, Technical Support and Capacity Building Programme, Thursday, 8 December Welcome and Registration 08:15 Registration 08:45 Welcome and Introduction, Christian Lengeler

6. Spring Symposium 2019 (Page)

   Spring Symposium 2019

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   Education, Vocational Training and Continuing Professional Development Swiss TPH Spring Symposium - 8 May 2019 - Parterre Rialto, Basel, Switzerland The availability of a well-trained and motivated health

7. Synthesis and antiprotozoal activity of aza-analogues of furamidine (Publications)

   Synthesis and antiprotozoal activity of aza-analogues of furamidine

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   e (T. b. r.) and P. falciparum (P. f.). The diamidines 8a, 8c, and 14b gave IC(50) values versus T. b. r. of less than 10 nM. Against P. f. 8a, 8b, and 14b exhibited IC(50) values less than 10 nM. In an [...] imide, followed by Suzuki coupling with 4-cyanophenylboronic acid. In a similar way, diamidines 8b and 8c were prepared from the dicyano derivatives 4c and 4d, respectively. N-Methoxy-6-[5-[4-(N-metho [...] 6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from...

8. Synthesis and antiprotozoal activity of aza-analogues of furamidine (Publications)

   Synthesis and antiprotozoal activity of aza-analogues of furamidine

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   e (T. b. r.) and P. falciparum (P. f.). The diamidines 8a, 8c, and 14b gave IC(50) values versus T. b. r. of less than 10 nM. Against P. f. 8a, 8b, and 14b exhibited IC(50) values less than 10 nM. In an [...] imide, followed by Suzuki coupling with 4-cyanophenylboronic acid. In a similar way, diamidines 8b and 8c were prepared from the dicyano derivatives 4c and 4d, respectively. N-Methoxy-6-[5-[4-(N-metho [...] 6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from...

9. Chloropupukeanolides C-E: cytotoxic pupukeanane chlorides with a spiroketal skeleton from <em>Pestalotiopsis fici</em> (Publications)

   Chloropupukeanolides C-E: cytotoxic pupukeanane chlorides with a spiroketal skeleton from <em>Pestalotiopsis fici</em>

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   The absolute configuration of 8 was assigned by X-ray crystallography and those of 9 and 10 by quantum-chemical CD calculations. Biogenetically, chloropupukeanolides C-E (8-10) are presumably derived from [...] configurations of the complete "Southern parts" of 8 and 9 suggests that this Diels-Alder reaction is stereochemically not very selective. Compounds 8-10 showed significant cytotoxicity against a small [...] Chloropupukeanolides C-E (8-10), three highly functionalized secondary...

10. Chloropupukeanolides C-E: cytotoxic pupukeanane chlorides with a spiroketal skeleton from <em>Pestalotiopsis fici</em> (Publications)

    Chloropupukeanolides C-E: cytotoxic pupukeanane chlorides with a spiroketal skeleton from <em>Pestalotiopsis fici</em>

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    The absolute configuration of 8 was assigned by X-ray crystallography and those of 9 and 10 by quantum-chemical CD calculations. Biogenetically, chloropupukeanolides C-E (8-10) are presumably derived from [...] configurations of the complete "Southern parts" of 8 and 9 suggests that this Diels-Alder reaction is stereochemically not very selective. Compounds 8-10 showed significant cytotoxicity against a small [...] Chloropupukeanolides C-E (8-10), three highly functionalized secondary...