Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of <em>Klebsiella oxytoca</em> group in invasive infections: a retrospective... (Publications)
quasipneumoniae (3.3%; n = 575), K. variicola (9.8%; n = 1717), "K. quasivariicola" (0.3%; n = 52), K. oxytoca (8.2%; n = 1445), K. michiganensis (4.8%; n = 836), K. grimontii (2.4%; n = 425) and K. huaxensis
Efficacy and safety of ascending doses of moxidectin against<em> Strongyloides stercoralis</em> infections in adults: a randomised, parallel-group,... (Publications)
randomisation into seven treatment groups: 2 mg of moxidectin, 4 mg of moxidectin, 6 mg of moxidectin, 8 mg of moxidectin, 10 mg of moxidectin, 12 mg of moxidectin, or placebo. Participants and primary outcome [...] cured) at 4 mg to 86% (79-90; 27 [84%] of 32 cured) at 6 mg, and to 87% (80-92; 24 [83%] of 29 cured) at 8 mg, levelling off at 88% (80-93; 29 [97%] of 30 cured) at 10 mg and 88% (80-93; 26 [87%] of 30 cured) [...] tolerability and efficacy profiles in the treatment of S stercoralis...
Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015 (Publications)
indices. FINDINGS: In 2015, the median health-related SDG index was 59.3 (95% uncertainty interval 56.8-61.8) and varied widely by country, ranging from 85.5 (84.2-86.5) in Iceland to 20.4 (15.4-24.9) in Central [...] (a median change of 10.0 [6.7-13.1]) exceeded that of the non-MDG index (a median change of 5.5 [2.1-8.9]). Since 2000, pronounced progress occurred for indicators such as met need with modern contraception
Global, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019 (Publications)
(0·947-1·71) in 2019. Age-standardised mortality rates decreased from 7·5 (6·6-8·4) per 100 000 population in 1990 to 3·3 (2·8-3·9) per 100 000 population in 2019. The highest proportion of total all-age [...] showed the largest reduction in the number of deaths among children younger than 5 years (76·5% [69·5-81·8]), followed by N meningitidis (72·3% [64·4-78·5]) and viruses (58·2% [47·1-67·3]). INTERPRETATION:
Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of <em>Klebsiella oxytoca</em> group in invasive infections: a retrospective... (Publications)
quasipneumoniae (3.3%; n = 575), K. variicola (9.8%; n = 1717), "K. quasivariicola" (0.3%; n = 52), K. oxytoca (8.2%; n = 1445), K. michiganensis (4.8%; n = 836), K. grimontii (2.4%; n = 425) and K. huaxensis
Efficacy and safety of ascending doses of moxidectin against<em> Strongyloides stercoralis</em> infections in adults: a randomised, parallel-group,... (Publications)
randomisation into seven treatment groups: 2 mg of moxidectin, 4 mg of moxidectin, 6 mg of moxidectin, 8 mg of moxidectin, 10 mg of moxidectin, 12 mg of moxidectin, or placebo. Participants and primary outcome [...] cured) at 4 mg to 86% (79-90; 27 [84%] of 32 cured) at 6 mg, and to 87% (80-92; 24 [83%] of 29 cured) at 8 mg, levelling off at 88% (80-93; 29 [97%] of 30 cured) at 10 mg and 88% (80-93; 26 [87%] of 30 cured) [...] tolerability and efficacy profiles in the treatment of S stercoralis...
Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015 (Publications)
indices. FINDINGS: In 2015, the median health-related SDG index was 59.3 (95% uncertainty interval 56.8-61.8) and varied widely by country, ranging from 85.5 (84.2-86.5) in Iceland to 20.4 (15.4-24.9) in Central [...] (a median change of 10.0 [6.7-13.1]) exceeded that of the non-MDG index (a median change of 5.5 [2.1-8.9]). Since 2000, pronounced progress occurred for indicators such as met need with modern contraception
Impact of the warm summer 2015 on emergency hospital admissions in Switzerland (Publications)
Highest excess EHA estimates were found in the warmest regions (Ticino [8.4%, 95% CI 5.1-11.7%] and the Lake Geneva region [4.8%, 95% CI 3.0-6.7%]) and among the elderly population aged > /=75 years (5
Carriage of linezolid-resistant enterococci (LRE) among humans and animals in Nigeria: coexistence of the <em>cfr, optrA </em>and <em>poxtA</em> genes... (Publications)
LRE were recovered from 5.87% (37/630; 95% CI:4.17 - 8.00) of the samples with the prevalence in animals and humans being 6.22% (28/450); 95%CI:4.17-8.87) and 5.00% (9/180); 95% CI:2.31-9.28 respectively
Decreasing incidence of conjunctival squamous cell carcinoma in people with HIV in South Africa (Publications)
overall SCCC incidence rate of 6.8/100,000 person-years. The SCCC incidence rate decreased between 2004 and 2014 with an annual percentage change of -10.9% (95% CI -13.3 to -8.3). PWH residing within latitudes
