Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990-2021: findings from the Global... (Publications)
(36·3-53·1) for the same period (down from 4·03 million [3·86-4·22] neonatal deaths in 1990). Stillbirths in south Asia and sub-Saharan Africa comprised 77·4% (2·35 million of 3·04 million) of the global [...] and 10 585 unique location-year combinations from vital registration systems. Our final dataset comprised 11 different definitions, which were adjusted to match two gestational age thresholds: 20 weeks [...] neonatal deaths. The estimated number of stillbirths occurring at 20 weeks'...
Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey (Publications)
Community Respiratory Health Survey. METHODS: General population samples aged 20-44 were randomly selected in 1991-1993 and followed up 20 years later (2010-2012). Spirometry was performed at baseline and at follow-up [...] FINDINGS: 3343 participants fulfilled the inclusion criteria; 89 of them had COPD at follow-up (1.4 cases/1000 person-years). Participants exposed to biological dust had a higher incidence of COPD compared [...] (relative risk (RR) 1.6, 95% CI 1.1 to 2.3), as did those...
Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey (Publications)
Community Respiratory Health Survey. METHODS: General population samples aged 20-44 were randomly selected in 1991-1993 and followed up 20 years later (2010-2012). Spirometry was performed at baseline and at follow-up [...] FINDINGS: 3343 participants fulfilled the inclusion criteria; 89 of them had COPD at follow-up (1.4 cases/1000 person-years). Participants exposed to biological dust had a higher incidence of COPD compared [...] (relative risk (RR) 1.6, 95% CI 1.1 to 2.3), as did those...
Travellers' profile, travel patterns and vaccine practices - a 10-year prospective study in a Swiss Travel Clinic (Publications)
Asia, 20% to Latin America and 1% (each) to Oceania and Europe; 19% visited more than one country. India was the most common destination (9.6% of travellers) followed by Thailand (8.6%) and Kenya (6.4%).
Travellers' profile, travel patterns and vaccine practices - a 10-year prospective study in a Swiss Travel Clinic (Publications)
Asia, 20% to Latin America and 1% (each) to Oceania and Europe; 19% visited more than one country. India was the most common destination (9.6% of travellers) followed by Thailand (8.6%) and Kenya (6.4%).
Long-term exposure to traffic-related PM10 and decreased heart rate variability: is the association restricted to subjects taking ACE inhibitors? (Publications)
only associated with TPM(10) in participants under ACE inhibitor therapy (N=94). A 1mug/m(3) increment, approximately equivalent to an interquartile range, in 10year average TPM(10) was associated with decrements [...] (HF) power, of 4.5% (-8.2 to -0.5) in the standard deviation of all normal-to-normal RR intervals (SDNN), of 10.6% (-18.5 to -1.9) in total power (TP) and an increase of 9.2% (0.8 to 20.2) in the LF/HF [...] cardiovascular mortality. OBJECTIVES: We investigated whether long-term...
Long-term exposure to traffic-related PM10 and decreased heart rate variability: is the association restricted to subjects taking ACE inhibitors? (Publications)
only associated with TPM(10) in participants under ACE inhibitor therapy (N=94). A 1mug/m(3) increment, approximately equivalent to an interquartile range, in 10year average TPM(10) was associated with decrements [...] (HF) power, of 4.5% (-8.2 to -0.5) in the standard deviation of all normal-to-normal RR intervals (SDNN), of 10.6% (-18.5 to -1.9) in total power (TP) and an increase of 9.2% (0.8 to 20.2) in the LF/HF [...] cardiovascular mortality. OBJECTIVES: We investigated whether long-term...
Creation of the WHO Indicators of Infant and Young Child Development (IYCD): metadata synthesis across 10 countries (Publications)
development outcomes, as evidenced by the focus of the United Nations Sustainable Development Goal 4, highlights an increased need for reliable and valid measures to evaluate preventive and interventional [...] metadata synthesis. Methods: Fourteen cross-sectional data sets were contributed on 21 083 children from 10 low/middle-income countries (LMIC), assessed using seven different tools (caregiver reported or directly [...] 50 items identified at second mapping. A tool comprising 120 items (23...
Creation of the WHO Indicators of Infant and Young Child Development (IYCD): metadata synthesis across 10 countries (Publications)
development outcomes, as evidenced by the focus of the United Nations Sustainable Development Goal 4, highlights an increased need for reliable and valid measures to evaluate preventive and interventional [...] metadata synthesis. Methods: Fourteen cross-sectional data sets were contributed on 21 083 children from 10 low/middle-income countries (LMIC), assessed using seven different tools (caregiver reported or directly [...] 50 items identified at second mapping. A tool comprising 120 items (23...
HIV infection functionally impairs <em>Mycobacterium tuberculosis</em>-specific CD4 and CD8 T-cell responses (Publications)
significantly reduced the proportion of Th2 (IL-4/IL-5/IL-13) producing Mtb-specific CD4 T cells and IL-2 producing Mtb-specific CD4 and CD8 T cells in both individuals with LTBI or PTB (P [...] that progression from LTBI to pulmonary TB (PTB) might not only be due to CD4 T-cell depletion but also to Mtb-specific CD4 T-cell functional impairment. To test this hypothesis, Mtb-specific T-cell f [...] Tanzanian individuals suffering from LTBI (n=20) or PTB (n=67) and compared to those of untreated...