Dr. Nicolas Brancucci

Function(s)
Head of Unit

Organisational Entity

 

Bui H.T.N, Niederwieser I, Bird M.J, Dai W, Brancucci N.M.B, Moes S, Jenoe P, Lucet I.S, Doerig C, Voss T.S. Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum. Sci Rep. 2019;9:16720. DOI: 10.1038/s41598-019-53325-9

De Niz M, Meibalan E, Mejia P, Ma S, Brancucci N.M.B, Agop-Nersesian C, Mandt R, Ngotho P, Hughes K.R, Waters A.P, Huttenhower C, Mitchell J.R, Martinelli R, Frischknecht F, Seydel K.B, Taylor T, Milner D, Heussler V.T, Marti M. Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow. Sci Adv. 2018;4(5):eaat3775. DOI: 10.1126/sciadv.aat3775

Brancucci N.M.B, Gerdt J.P, Wang C, De Niz M, Philip N, Adapa S.R, Zhang M, Hitz E, Niederwieser I, Boltryk S.D, Laffitte M.C, Clark M.A, Gruring C, Ravel D, Blancke Soares A, Demas A, Bopp S, Rubio-Ruiz B, Conejo-Garcia A, Wirth D.F, Gendaszewska-Darmach E, Duraisingh M.T, Adams J.H, Voss T.S, Waters A.P, Jiang R.H.Y, Clardy J, Marti M. Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum. Cell. 2017;171(7):1532-1544 e15. DOI: 10.1016/j.cell.2017.10.020

Kato N, Comer E, Sakata-Kato T, Sharma A, Sharma M, Maetani M, Bastien J, Brancucci N.M, Bittker J.A, Corey V, Clarke D, Derbyshire E.R, Dornan G.L, Duffy S, Eckley S, Itoe M.A, Koolen K.M, Lewis T.A, Lui P.S, Lukens A.K, Lund E, March S, Meibalan E, Meier B.C, McPhail J.A, Mitasev B, Moss E.L, Sayes M, Van Gessel Y, Wawer M.J, Yoshinaga T, Zeeman A.M, Avery V.M, Bhatia S.N, Burke J.E, Catteruccia F, Clardy J.C, Clemons P.A, Dechering K.J, Duvall J.R, Foley M.A, Gusovsky F, Kocken C.H, Marti M, Morningstar M.L, Munoz B, Neafsey D.E, Sharma A, Winzeler E.A, Wirth D.F, Scherer C.A, Schreiber S.L. Diversity-oriented synthesis yields novel multistage antimalarial inhibitors. Nature. 2016;538(7625):344-349. DOI: 10.1038/nature19804

Mantel P.Y, Hjelmqvist D, Walch M, Kharoubi-Hess S, Nilsson S, Ravel D, Ribeiro M, Gruring C, Ma S, Padmanabhan P, Trachtenberg A, Ankarklev J, Brancucci N.M, Huttenhower C, Duraisingh M.T, Ghiran I, Kuo W.P, Filgueira L, Martinelli R, Marti M. Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria. Nat Commun. 2016;7:12727. DOI: 10.1038/ncomms12727

Brancucci N.M, Goldowitz I, Buchholz K, Werling K, Marti M. An assay to probe Plasmodium falciparum growth, transmission stage formation and early gametocyte development. Nat Protoc. 2015;10(8):1131-42. DOI: 10.1038/nprot.2015.072

Dantzler K.W, Ravel D.B, Brancucci N.M, Marti M. Ensuring transmission through dynamic host environments: host-pathogen interactions in Plasmodium sexual development. Curr Opin Microbiol. 2015;26:17-23. DOI: 10.1016/j.mib.2015.03.005

Ankarklev J, Brancucci N.M, Goldowitz I, Mantel P.Y, Marti M. Sex: how malaria parasites get turned on. Curr Biol. 2014;24(9):R368-70. DOI: 10.1016/j.cub.2014.03.046