DAVINCI - Development and Validation of a Laminar Flow Test to Diagnose COVID-19 in Saliva

This project addresses the currently crucial needs in the area of validated point-of-care (PoC) diagnostics for use at every level in the population. We will develop and validate a simple inexpensive accurate rapid diagnostic test using the easily accessible non-invasive sample specimen saliva and address the much needed necessity of large-scale testing and delineating the extent of seroprevalence and herd immunity in the population. We will evaluate the utility of saliva in COVID-19 patients, contributing to the understanding of IgG/IgM/IgA antibody presence, isotypes and their dynamics in saliva during infection and compare these to antibody profiles in blood. The home-based test design to diagnose COVID-19 incorporates an application for digitalized capture of the test result to rapidly collate diagnoses assigned to geo-location. Importantly, the test and application provide a platform that is easily translated into the real-world and is easily scalable in a local, national and international network to improve health care and public health measures during and beyond the pandemic.

Contact

Daniel Paris

Prof. Dr. med. Daniel Paris, Associate Professor, MD, PhD, DTMH
Head of Department, Medical Director

0612848111
daniel.parisswisstph.ch

Project Facts