China's sustained drive to eliminate neglected tropical diseases (Publications)
infected. China harbours more than 90% of the world's burden of alveolar echinococcosis and food-borne zoonoses are emerging. In 2010, the overall prevalence of soil-transmitted helminth infections caused [...] Non-communicable diseases dominate the public health arena in China, yet neglected tropical diseases (NTDs) are still widespread and create a substantial burden. We review the geographical distribution [...] characteristics of NTDs identified in China caused by helminths, protozoa,...
Polyparasitism with <em>Schistosoma mansoni,</em> geohelminths, and intestinal protozoa in rural Côte d'Ivoire (Publications)
common over large parts of sub-Saharan Africa, and it is expected that polyparasitism affects a considerable proportion of the population, hence posing a great toll on public health. However, few investigations [...] prevalences of 71.5, 64.6, and 51.9%, respectively. Only 8 individuals displayed no infection, whereas two-thirds of the population harbored 3 or more parasites concurrently. There were a series of significant [...] investigations have been carried out to quantify the extent of...
The drugs we have and the drugs we need against major helminth infections (Publications)
control and elimination as a public health problem. Regular administration of anthelminthic drugs to at-risk populations (e.g. school-aged children) serves as the backbone of interventions in areas where [...] thousands of years and, still today, they are pervasive where poverty persists, including large parts of Southeast Asia and the Western Pacific Region. The global strategy for the control of helminth [...] recent advances made with anthelminthic drugs that might become the future...
Subtle to severe hepatobiliary morbidity in <em>Opisthorchis viverrini </em>endemic settings in Southern Laos (Publications)
range. The number of CCA suspected liver masses and hepatobiliary morbidity diagnosed among clinically asymptomatic adult patients in O. viverrini endemic areas presents a major public health concern in Laos [...] A random sample of 431 O. viverrini patients from 10 villages underwent abdominal US. Mild, moderate and markedly advanced periductal fibrosis was diagnosed in 7.0%, 66.5%, and 17.0% of patients, respectively [...] respectively. Normal liver parenchyma was seen in only 9.5% of...
Controlling schistosomiasis with praziquantel: how much longer without a viable alternative? (Publications)
The current approach of morbidity control of schistosomiasis, a helminth disease of poverty with considerable public health and socioeconomic impact, is based on preventive chemotherapy with praziquantel [...] authorities. The antischistosomal properties of antimalarial drugs (e.g., semisynthetic artemisinins, synthetic trioxolanes, trioxaquines and mefloquine) and of drugs being developed or registered for other [...] recent progress made in schistosomiasis chemotherapy, placing particular...
Estimating particulate exposure from modern municipal waste incinerators in Great Britain (Publications)
European Union Directive on Industrial Emissions (IED), but there is ongoing public concern regarding potential hazards to health. Using dispersion modeling, we estimated spatial variability in PM10 conc [...] (average 12 households) within 10 km of MWIs in Great Britain (GB) in 2003-2010. We also investigated change points in PM10 emissions in relation to introduction of EU Waste Incineration Directive (EU-WID) [...] were typically 6.59-2.68 x 101 mug m-3, 3-5 orders of magnitude higher. While...
Software application profile: opal and mica: open-source software solutions for epidemiological data management, harmonization and dissemination (Publications)
Improving the dissemination of information on existing epidemiological studies and facilitating the interoperability of study databases are essential to maximizing the use of resources and accelerating [...] improvements in health. To address this, Maelstrom Research proposes Opal and Mica, two inter-operable open-source software packages providing out-of-the-box solutions for epidemiological data management [...] Availability: Opal and Mica are open-source and freely available at [...
The Swiss 5G Backpacker: Hiking Across Switzerland to Explore EMF (Page)
https://www.swisstph.ch/de/impact-stories/the-swiss-5g-backpacker-hiking-across-switzerland-to-explore-electromagnetic-fields
Epidemiology and Public Health Department at Swiss TPH, is deeply interested in exploring the impact of society’s growing digitalization on both health and the environment. His PhD project consists of realizing [...] transport. The accumulation of such artificial EMF in the environment is also known as “electrosmog”. The introduction of new mobile communication technologies like 5G (the 5th generation of mobile communication [...] neighbourhoods), public spaces (e.g. tram stops), and public...
Bayesian Modelling and Analysis (Page)
https://www.swisstph.ch/de/about/eph/biostatistics/bayesian-modelling-and-analysis
areas of our research are spatio-temporal modelling and forecasting, modelling of multivariate data, including prediction of model uncertainty. Spatio-temporal modelling is a focal research area of the group [...] Group | Bayesian Modelling and Analysis Predicted Risk Map of Malaria Parasite among Children under 5 year in Nigeria Epidemiology and Public Health Biostatistics Biostatistics Frequentist modelling Bayesian [...] modelling of air pollution burden in Europe: integrating data from...
Parasite Chemotherapy (Page)
https://www.swisstph.ch/de/about/mpi/parasite-chemotherapy
Another element of the activities is to study the transmission of trypanosomes by the tsetse fly vector in order to gain more knowledge about the life cycle of the parasite and the function of certain surface [...] All Projects SNF_FP_modelling - Multi-scale mathematical modelling of parasite, drug and vaccine interactions: optimising public health and disease elimination strategies Latest Publications All Publications [...] Publications Corbel V et al. A new WHO bottle bioassay method to assess...