Implementation research of a cluster randomized trial evaluating the implementation and effectiveness of intermittent preventive treatment for malaria... (Publications)
since the malaria epidemiologic shift to school-aged children was noted. In the meantime, school-aged children (5-15 years) have become increasingly more vulnerable with asymptomatic malaria prevalence [...] to 70%, making them reservoirs for subsequent transmission of malaria in the endemic communities. Intermittent Preventive Treatment of malaria in schoolchildren (IPTsc) has proven to be an effective tool [...] Tanzania so as to understand the operational feasibility and effectiveness of...
OpenMalaria Workflow and OpenMalariaUtilities R Packages (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/openmalaria-workflow-and-openmalariautilities-r-packages
Swiss TPH GitHub . OpenMalariaUtilities R Package At the core of our OpenMalaria Workflow is the OpenMalariaUtilities R package which is developed to allow the use of OpenMalaria directly from R. The package [...] OpenMalaria Workflow R Package The work of the Analytics and Intervention Modelling Group is based on OpenMalaria : an open-source C++ program for simulating malaria epidemiology and the impacts on that [...] TPH GitHub. The OpenMalaria Workflow R Package together with the OpenMalariaU...
Attitudes, practices, and determinants of community care-seeking behaviours for fever/malaria episodes in the context of the implementation of... (Publications)
FGDs showed that participants had good knowledge about malaria symptoms, prevention tools, and effective treatment. Behaviour change regarding malaria treatment and free medication for children under five [...] CONCLUSIONS: The study showed appropriate knowledge about malaria and positive community care-seeking behaviour at health centres for fever/malaria episodes. This could potentially facilitate the implementation [...] BACKGROUND: Malaria case management relies on World Health Organization...
Reflections on the 2021 World Malaria Report and the future of malaria control (Publications)
The World Malaria Report, released in December 2021, reflects the unique challenges currently facing the global malaria community. The report showed the devastating toll of malaria, with an estimated 627 [...] the capacity of the continent to address the malaria challenge. African countries also face a convergence of biological threats that could redefine malaria control, notably widespread pyrethroid resistance [...] presents key insights from the 2021 World Malaria Report and reflections on...
Scoping Study for a Strategic Environmental Assessment (SEASS) on the potential operational use of gene drive in the main malaria-carrying Anopheles... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/scoping-study-for-a-strategic-environmental-assessment-seass-on-the-potential-operational-use-of-gene-drive-in-the-main-malaria-carrying-anopheles-mosquito-species-in-west-africa-on-behalf-of-target-malaria
Target Malaria isa not-for-profit research consortium that aims to develop and share new, cost-effective, and sustainable genetic technologies to modify mosquitoes and reduce malaria transmission. The [...] The intervention which is currently in development by Target Malaria (i.e. a population suppression gene drive) works by reducing the ability of female mosquitoes to reproduce through non-mendelian inheritance [...] inheritance of an introduced gene targeting female fertility, thereby...
Child Health and Infection with Low Density (CHILD) Malaria, a randomized controlled trial to assess the long-term health and socioeconomic impact of... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/child-health-and-infection-with-low-density-child-malaria-a-randomized-controlled-trial-to-assess-the-long-term-health-and-socioeconomic-impact-of-interventions-targeting-low-density-malaria-infection-lmi-among-children-in-tanzania
As malaria transmission declines, an increasing proportion of infections persist in the body at low levels. Low-density malaria infection (LMI) are often chronic and represent a high proportion of infections [...] they may provide protective immunity again future malaria illness. There is a growing body evidence to suggest that LMI are associated with recurrent malaria, chronic anemia, poor growth, co-infection with [...] for malaria (using RDT and qPCR) three times annually, with AL...
Malaria control across borders: quasi-experimental evidence from the Trans-Kunene malaria initiative (TKMI) (Publications)
BACKGROUND: The transmission of malaria through population inflows from highly endemic areas with limited control efforts poses major challenges for national malaria control programmes. Several multilateral [...] l efforts. CONCLUSIONS: The impact of malaria programmes depends on programme efforts in surrounding areas with differential control efforts. Coordinated malaria programming within and across countries [...] the potential impact of such a programme at the Angolan-Namibian border....
