Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with <em>Fasciola hepatica</em> (Publications)
The pharmacokinetic (PK) parameters of artesunate, artemether and their metabolites dihydroartemisinin (DHA) and dihydroartemisinin-glucuronide (DHA-glucuronide) were determined in sheep naturally inf
Opposite effects of CD14/-260 on serum IgE levels in children raised in different environments (Publications)
BACKGROUND: Most complex diseases are the result of interactions between polymorphisms in the genome and environmental exposures. OBJECTIVE: We sought to investigate the previously reported associatio
Abietane diterpenoids from <em>Salvia sahendica</em> - antiprotozoal activity and determination of their absolute configurations (Publications)
In a screening of Iranian plants for antiprotozoal activity, an n-hexane extract of the roots of Salvia sahendica potently inhibited the growth of Plasmodium falciparum K1 strain. Subsequent HPLC-base
Development and validation of a clinical decision rule for the diagnosis of influenza (Publications)
INTRODUCTION: A clinical decision rule to improve the accuracy of a diagnosis of influenza could help clinicians avoid unnecessary use of diagnostic tests and treatments. Our objective was to develop
Effectiveness of dog rabies vaccination programmes: comparison of owner-charged and free vaccination campaigns (Publications)
We investigated the percentage of dogs that could be vaccinated against rabies by conducting a pilot campaign in N'Djamena, Chad. Owners were charged US$4.13 per dog vaccinated, and 24% of all dogs in
The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone (Publications)
An unsaturated dispiro 1,2,4,5-tetraoxane formed by peroxidation of (+)-dihydrocarvone was converted into four structurally diverse derivatives. X-ray crystallographic analysis shows that the structur