Drug discovery for kinetoplastid diseases: future directions (Publications)
Kinetoplastid parasites have caused human disease for millennia. Significant achievements have been made toward developing new treatments for leishmaniasis (particularly on the Indian subcontinent) an
HIV infection functionally impairs <em>Mycobacterium tuberculosis</em>-specific CD4 and CD8 T-cell responses (Publications)
HIV infection is the major risk factor predisposing for Mycobacterium tuberculosis (Mtb) progression from latent tuberculosis infection (LTBI) to tuberculosis disease (TB). Since long-term treated avi
SAR of a new antischistosomal urea carboxylic acid (Publications)
Urea carboxylic acids, products of aryl hydantoin hydrolysis, were recently identified as a new antischistosomal chemotype. We now describe a baseline structure-activity relationship (SAR) for this co
Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic: a cross-sectional study (Publications)
BACKGROUND: As a result of epidemiological transition, the health systems of low- and middle-income countries are increasingly faced with a dual disease burden of infectious diseases and emerging non-
What conditions enable decentralization to improve the health system? Qualitative analysis of perspectives on decision space after 25 years of... (Publications)
BACKGROUND: Decentralization is promoted as a strategy to improve health system performance by bringing decision-making closer to service delivery. Some studies have investigated if decentralization a
Using open street map data in environmental exposure assessment studies: Eastern Massachusetts, Bern region, and South Israel as a case study (Publications)
There is an increase in the awareness of the importance of spatial data in epidemiology and exposure assessment (EA) studies. Most studies use governmental and ordnance surveys, which are often expens