Papua New Guinea National Malaria Control Programme Evaluation and Operational Research 2021 to 2023 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/papua-new-guinea-national-malaria-control-programme-evaluation-and-operational-research-2021-to-2023
exhibits a complex malaria epidemiology with marked heterogeneity in malaria transmission. With financial support from the Global Fund to Fight AIDS, Tuberculosis and Malaria, the National Malaria Control Program [...] across PNG to assess quality of malaria case management. Activity 2: a national Malaria Indicator Survey (MIS) to track progress in malaria intervention coverage and malaria prevalence on national and regional [...] changing malaria epidemiology in PNG (including aspects related...
Species composition and insecticide resistance in malaria vectors in Ellibou, southern Côte d’Ivoire and first finding of <em>Anopheles... (Publications)
status of the target vector population is important to guide malaria vector control. The aim of this study was to characterize the malaria vector population in terms of species composition, insecticide [...] an early warning sign, as An. arabiensis shows a different biology than the currently documented malaria vectors. Because the local An. gambiae population was still susceptible to malathion, upregulation
The relative effect of climate variability on malaria incidence after scale-up of interventions in western Kenya: a time-series analysis of monthly... (Publications)
effect of climate variability on malaria incidence after scale-up of interventions in western Kenya. Methods Bayesian negative binomial models were fitted to monthly malaria incidence data, extracted from [...] variable selection was used to determine the elapsing time between climate suitability and malaria incidence. Results Malaria incidence increased by 50% from 2008 to 2010, then declined by 73% until 2015. There [...] associated with a decline in malaria incidence in children aged 6–59...
Modelling to inform next-generation medical interventions for malaria prevention and treatment (Publications)
Global progress against malaria has stagnated and novel medical interventions to prevent malaria are needed to fill gaps in existing tools and improve protection against infection and disease. Candidate [...] opportunity to link product characteristics with expected public health outcomes. Population models of malaria transmission can provide a better understanding of which, and at what magnitude, key intervention [...] deployment strategies. We describe how modelling evidence can guide and...
What Africa can do to accelerate and sustain progress against malaria (Publications)
weaknesses in the fight against malaria and instead reinforces a narrow, commodity-driven vision of disease control. This paper therefore describes the core challenges hindering malaria programs in Africa and [...] After a longstanding global presence, malaria is now largely non-existent or suppressed in most parts of the world. Today, cases and deaths are primarily concentrated in sub-Saharan Africa. According to [...] opportunities to rethink current strategies for sustainable control and...
Model-informed target product profiles of long-acting-injectables for use as seasonal malaria prevention (Publications)
Seasonal malaria chemoprevention (SMC) has proven highly efficacious in reducing malaria incidence. However, the continued success of SMC is threatened by the spread of resistance against one of its main [...] and incomplete adherence to the regimens. Via a simulation study with an individual-based model of malaria dynamics, we provide quantitative evidence to assess long-acting injectables (LAIs) as potential
Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic... (Publications)
concerns about an effective continuum of care for children with severe malaria seem justified. Stricter compliance with the WHO severe malaria treatment guidelines is critical to effectively manage this disease [...] BACKGROUND: For a full treatment course of severe malaria, community-administered pre-referral rectal artesunate (RAS) should be completed by post-referral treatment consisting of an injectable antimalarial [...] admission in included referral health facilities (RHFs) in children...
Identifying individual, household and environmental risk factors for malaria infection on Bioko Island to inform interventions (Publications)
BACKGROUND: Since 2004, malaria transmission on Bioko Island has declined significantly as a result of the scaling-up of control interventions. The aim of eliminating malaria from the Island remains elusive [...] 2015 and 2018 annual malaria indicator surveys on Bioko Island, as well as remotely-sensed environmental data in multilevel logistic regression models to quantify the odds of malaria infection. The analyses [...] significantly the odds of malaria across urban and rural settings and...
Treatment-seeking for children with suspected severe malaria attending community health workers and primary health centres in Adamawa State, Nigeria (Publications)
The Community Access to Rectal Artesunate for Malaria project investigated the feasibility of introducing pre-referral rectal artesunate into existing community-based health services. In that study, the
