Searched for malaria.

1. Assessing determinants of programmatic performance of community management of malaria, pneumonia, and diarrhea in children in Africa: protocol and... (Publications)

   Assessing determinants of programmatic performance of community management of malaria, pneumonia, and diarrhea in children in Africa: protocol and data collection for a mixed methods evaluation of integrated community case management

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   health program designed to provide integrated community-based care for children with pneumonia, malaria, or diarrhea in hard-to-reach areas of low- and middle-income countries. The foundation of the i

2. Haematological consequences of acute uncomplicated <em>falciparum </em>malaria: a WorldWide Antimalarial Resistance Network pooled analysis of... (Publications)

   Haematological consequences of acute uncomplicated <em>falciparum </em>malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data

   Relevance:

   falciparum malaria to identify the factors associated with malarial anaemia. METHODS: Individual patient data from eligible antimalarial efficacy studies of uncomplicated P. falciparum malaria, available [...] BACKGROUND: Plasmodium falciparum malaria is associated with anaemia-related morbidity, attributable to host, parasite and drug factors. We quantified the haematological response following treatment of [...] = 2.06 [95%CI 1.39-3.05], p < 0.001). CONCLUSIONS: In patients with uncomplicated...

3. Geostatistical modelling and survey sampling designs for malaria control and surveillance (Publications)

   Geostatistical modelling and survey sampling designs for malaria control and surveillance

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4. Improving malaria control by understanding human behaviour (Publications)

   Improving malaria control by understanding human behaviour

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5. Volunteer infection studies accelerate the clinical development of novel drugs against malaria (Publications)

   Volunteer infection studies accelerate the clinical development of novel drugs against malaria

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6. Mathematical modelling of malaria control interventions to support strategic planning in Tanzania (Publications)

   Mathematical modelling of malaria control interventions to support strategic planning in Tanzania

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7. Characterising co-infections with <em>Plasmodium </em>spp., <em>Mansonella perstans</em> or <em>Loa loa </em>in asymptomatic children, adults and... (Publications)

   Characterising co-infections with <em>Plasmodium </em>spp., <em>Mansonella perstans</em> or <em>Loa loa </em>in asymptomatic children, adults and elderly people living on Bioko Island using nucleic acids extracted from malaria rapid diagnostic tests

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   Equatorial Guinea are lacking. We aimed to demonstrate that blood retained on malaria rapid diagnostic tests, commonly deployed for malaria surveys, could be used as a source of nucleic acids for molecular based [...] with malaria in an asymptomatic population. METHODOLOGY: M. perstans, L. loa and Plasmodium spp. parasites were monitored by qPCR in a cross-sectional study using DNA extracted from a subset malaria rapid [...] rapid diagnostic tests (mRDTs) collected during the annual malaria...

8. Revisiting the effect of pharmaceuticals on transmission stage formation in the malaria parasite <em>Plasmodium falciparum</em> (Publications)

   Revisiting the effect of pharmaceuticals on transmission stage formation in the malaria parasite <em>Plasmodium falciparum</em>

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   Malaria parasites rely on specialized stages, called gametocytes, to ensure human-to-human transmission. The formation of these sexual precursor cells is initiated by commitment of blood stage parasites [...] vivo. These observations suggest that therapeutic interventions may promote gametocytogenesis and malaria transmission. Here, we engineered a P. falciparum reporter line to quantify sexual commitment rates [...] rates after exposure to antimalarials and other pharmaceuticals commonly...

9. Molecular measures for declining malaria transmission in Papua New Guinea (Publications)

   Molecular measures for declining malaria transmission in Papua New Guinea

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10. Characterization of field malaria isolates and assessment of the impact of resistance profile on the transmission of resistant strains (Projects)

    Characterization of field malaria isolates and assessment of the impact of resistance profile on the transmission of resistant strains

    Relevance:
    https://www.swisstph.ch/en/projects/project-detail/project/characterization-of-field-malaria-isolates-and-assessment-of-the-impact-of-resistance-profile-on-the-transmission-of-resistant-strains

    field malaria parasites, in order to provide a more realistic representation of malaria transmission occurring in natural settings. We will establish a continuous culture protocol for field malaria parasite [...] Health Institute (IHI, Tanzania). Malaria elimination is threatened by resistance to current insecticides and antimalarials. Developing novel technologies that target malaria transmission, such as transmission [...] transmission blocking drugs, vaccines or insecticides to control malari...