Searched for malaria.

1. A malaria-free China: global importance and key experience (Publications)

   A malaria-free China: global importance and key experience

   Relevance:

   Global Technical Strategy for Malaria 2016-2030 issued by the World Health Organization (WHO). China succeeded in its malaria elimination programme after being certified as malaria-free by the WHO on 30 June [...] Malaria has a worldwide distribution and is the world's deadliest mosquito-borne disease. The goal of malaria elimination is also reflected in the United Nations Sustainable Development Goals and the Global [...] l and socioeconomic characteristics, in order to present strong...

2. Prereferral rectal artesunate and referral completion among children with suspected severe malaria in the Democratic Republic of the Congo, Nigeria... (Publications)

   Prereferral rectal artesunate and referral completion among children with suspected severe malaria in the Democratic Republic of the Congo, Nigeria and Uganda

   Relevance:

   artesunate (RAS) require urgent referral to a health facility where appropriate treatment for severe malaria can be provided. However, the rapid improvement of a child's condition after RAS administration may [...] completion is limited. METHODS: An observational study accompanied the roll-out of RAS in three malaria endemic settings in the Democratic Republic of the Congo (DRC), Nigeria and Uganda. Community health [...] health workers and primary health centres enrolled children under 5...

3. Leveraging mathematical models of disease dynamics and machine learning to improve development of novel malaria interventions (Publications)

   Leveraging mathematical models of disease dynamics and machine learning to improve development of novel malaria interventions

   Relevance:

   targeted reductions in malaria prevalence. METHODS: A mathematical model of malaria transmission dynamics is used to simulate deployment and predict potential impact of new malaria interventions by considering [...] mathematical models of malaria dynamics coupled with machine learning. Our analysis identifies requirements of efficacy, coverage, and duration of effect for five novel malaria interventions to achieve [...] achieve specified health goals. RESULTS: We apply our approach to five malar...

4. Rethinking human resources and capacity building needs for malaria control and elimination in Africa (Publications)

   Rethinking human resources and capacity building needs for malaria control and elimination in Africa

   Relevance:

   considerable success in controlling malaria worldwide, progress toward achieving malaria elimination has largely stalled. In particular, strategies to overcome roadblocks in malaria control and elimination in Africa [...] Africa are critical to achieving worldwide malaria elimination goals—this continent carries 94% of the global malaria case burden. To identify key areas for targeted efforts, we combined a comprehensive [...] ve review of current literature with direct feedback gathered from...

5. Scalable process for high-yield production of PfCyRPA using insect cells for inclusion in a malaria virosome-based vaccine candidate (Publications)

   Scalable process for high-yield production of PfCyRPA using insect cells for inclusion in a malaria virosome-based vaccine candidate

   Relevance:

   been identified as a promising blood-stage candidate antigen to include in a broadly cross-reactive malaria vaccine. In the last couple of decades, substantial effort has been committed to the development [...] aiming to develop a scalable, high-yield, and high-quality PfCyRPA for inclusion in a virosome-based malaria vaccine candidate. Supplements with antioxidants improved PfCyRPA volumetric titers by 50% when added

6. Treatment seeking and case management for suspected severe malaria in the context of implementing rectal artesunate (Publications)

   Treatment seeking and case management for suspected severe malaria in the context of implementing rectal artesunate

   Relevance:

7. Next-generation malaria subunit vaccines to reduce disease burden in African children (Publications)

   Next-generation malaria subunit vaccines to reduce disease burden in African children

   Relevance:

8. The comprehensive multisectoral action framework: malaria and sustainable development (Publications)

   The comprehensive multisectoral action framework: malaria and sustainable development

   Relevance:

9. Determinants of patients' adherence to malaria treatment in the Democratic Republic of the Congo (Publications)

   Determinants of patients' adherence to malaria treatment in the Democratic Republic of the Congo

   Relevance:

   (1) Background: Malaria heavily affects the Democratic Republic of the Congo (DRC) despite the use of effective drugs. Poor adherence to malaria treatment may contribute to this problem. (2) Methods: In [...] the DRC, all households with a case of malaria in the 15 days preceding the survey were selected and the patients or caregivers were interviewed. Adherence to malaria treatment was assessed by self-declaration [...] urban area, university education, catholic religion, and adoption of...

10. Prevalence and force of <em>Plasmodium vivax</em> blood-stage infection and associated clinical malaria burden in the Brazilian Amazon (Publications)

    Prevalence and force of <em>Plasmodium vivax</em> blood-stage infection and associated clinical malaria burden in the Brazilian Amazon

    Relevance:

    Understanding the epidemiology of malaria through the molecular force of the blood-stage infection of Plasmodium vivax (molFOB) may provide a detailed assessment of malaria transmission. OBJECTIVES: In this [...] ed risk factors and spatial-temporal patterns of incidence of Plasmodium infection and clinical malaria episodes in three peri-urban communities of Manaus, Western Brazilian Amazon. METHODS: Monthly samples [...] Subjects who reported possession of a bed net [incidence rate ratio (IRR)...