An investment case to prevent the reintroduction of malaria in Sri Lanka (Publications)
in reducing the burden of malaria, recording no locally transmitted malaria cases since November 2012 and zero deaths since 2007. The country was recently certified as malaria free by World Health Organization [...] due to persistent receptivity and vulnerability to malaria transmission. Maintaining the gains will require continued sustainability to the malaria program to maintain the activities aimed at preventing [...] economic cost of the malaria program in 2014 was estimated at U.S. dollars...
Mefloquine at the crossroads? Implications for malaria chemoprophylaxis in Europa [Commentary] (Publications)
mefloquine. Some malaria prevention advisors question the scientific basis for the restrictions and suggest that this cost-effective, anti-malarial drug will be displaced as a first-line anti-malaria medication [...] the new recommendations for malaria prophylaxis that have been adapted by Switzerland, Germany, Austria and Italy where chemoprophylaxis use is restricted to high-risk malaria-endemic areas. [...] Since its introduction to the market in 1985, mefloquine has been used for malaria...
Malaria vectors and their blood-meal sources in an area of high bed net ownership in the western Kenya highlands (Publications)
BACKGROUND: Blood-meal sources of malaria vectors affect their capacity to transmit the disease. Most efficient malaria vectors prefer human hosts. However, with increasing personal protection measures [...] measures it becomes more difficult for them to find human hosts. Here recent malaria vector blood-meal sources in western Kenya highlands were investigated. METHODS: Adult mosquitoes resting indoors, outdoors [...] domesticated animals and 83.6 % had people sharing houses with livestock at...
Asymptomatic only at first sight: malaria infection among schoolchildren in highland Rwanda (Publications)
BACKGROUND: Plasmodium infection and malaria in school children are increasingly recognized as a relevant public health problem, but data on actual prevalence and health consequences are insufficient. [...] district of Rwanda, 1089 children aged 6-10 years were clinically and anthropometrically examined, malaria parasites were diagnosed by microscopy and PCR, haemoglobin concentrations were measured, and so [...] exception of underweight, these conditions were also increased at submicroscopic...
Malaria parasites possess a telomere repeat-binding protein that shares ancestry with transcription factor IIIA (Publications)
characteristic MYB-type domain. Here, we identified the telomere repeat-binding protein PfTRZ in the malaria parasite Plasmodium falciparum, a member of the Alveolate phylum for which TRFs have not been described
Spatial distribution of<em> Falciparum</em> malaria infections in Zanzibar: implications for focal drug administration strategies targeting... (Publications)
Background.: Optimal use of mass/targeted screen-and-treat or mass or focal drug administration as malaria elimination strategies remains unclear. We therefore studied spatial distribution of Plasmodium
Mosquito behavior change after distribution of bednets results in decreased protection against malaria exposure (Publications)
efficacy of vector control in reducing malaria transmission. Methods.: In this study, we quantified human exposure to both bites and infective bites of a major malaria vector in Papua New Guinea over the [...] the course of 4 years surrounding nationwide bednet distribution. We also quantified malaria infection prevalence in the human population during the same time period. Results.: We observed a shift in mosquito [...] period and was lowest in the adult population, who may be an important...