Estimating malaria transmission through mathematical models (Publications)
Evaluating the effectiveness of malaria control interventions on the basis of their impact on transmission is increasingly important as countries move from malaria control to pre-elimination programs. [...] Mathematical modeling can examine relationships between malaria indicators, allowing translation of easily measured data into measures of transmission, and addressing key concerns with traditional methods [...] Simulations show these indicators are statistically correlated, allowing direct...
High throughput multiplex assay for species identification of Papua New Guinea malaria vectors: members of the <em>Anopheles punctulatus</em>... (Publications)
Malaria and filariasis are transmitted in the Southwest Pacific region by Anopheles punctulatus sibling species including An. punctulatus, An. koliensis, the An. farauti complex 1-8 (includes An. hinesorum
Malaria mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites (Publications)
epidemiological differences in malaria mortality. RESULTS: Rates of malaria mortality varied by 1:10,000 across the sites, with generally low rates in Asia (one site recording no malaria deaths over 0.5 million [...] person-years). Childhood malaria mortality rates were strongly correlated with Malaria Atlas Project estimates of Plasmodium falciparum parasite rates for the same locations. Adult malaria mortality rates, while [...] BACKGROUND: Malaria continues to be a major cause of infectious...
Modeling the cost effectiveness of malaria control interventions in the highlands of western Kenya (Publications)
allow for in silico optimization of available malaria control strategies can assist the decision-making process for prioritizing interventions. The OpenMalaria stochastic simulation modeling platform can [...] Kenya, to support this goal. METHODS: Combinations of malaria interventions were simulated using a previously-published, validated model of malaria epidemiology and control in the study area. An economic [...] economic model of the costs of case management and malaria control interventions...
Effects of vector-control interventions on changes in risk of malaria parasiotaemia in sub-Saharan Africa: a spatial and temporal analysis (Publications)
episodes and deaths due to malaria have been mainly associated with the expansion of vector-control measures, such as insecticide-treated bednets and indoor residual spraying. Malaria indicator surveys gather [...] gather information about key malaria indicators through national representative household surveys. We aimed to estimate changes in risk of malaria parasitaemia at high spatial resolution in sub-Saharan Africa [...] that had publicly available data from two malaria indicator or...
Metabolic profiling framework for discovery of candidate diagnostic markers of malaria (Publications)
Despite immense efforts to combat malaria in tropical and sub-tropical regions, the potency of this vector-borne disease and its status as a major driver of morbidity and mortality remain undisputed. We
Assessing the relationship between environmental factors and malaria vector breeding sites in Swaziland using multi-scale remotely sensed data (Publications)
Many entomological studies have analyzed remotely sensed data to assess the relationship between malaria vector distribution and the associated environmental factors. However, the high cost of remotely
Geostatistical modelling of the malaria risk in Mozambique: effect of the spatial resolution when using remotely-sensed imagery (Publications)
literature exists on the relationship between malaria and environmental/climatic factors in different geographical areas, but few studies have linked human malaria parasitemia survey data with remote sensi [...] The study of malaria spatial epidemiology has benefited from recent advances in geographic information system and geostatistical modelling. Significant progress in earth observation technologies has led [...] classes and assess the effect of the spatial resolution of remotely sensed land...
