Lipidomics identifies a requirement for peroxisomal function during influenza virus replication (Publications)
Influenza virus acquires a host-derived lipid envelope during budding, yet a convergent view on the role of host lipid metabolism during infection is lacking. Using a mass spectrometry-based lipidomic
<em>In vitro</em> and<em> In vivo</em> evaluation of 28DAP010, a novel diamidine for treatment of second-stage African sleeping sickness (Publications)
African sleeping sickness is a neglected tropical disease transmitted by tsetse flies. New and better drugs are still needed especially for its second stage, which is fatal if untreated. 28DAP010, a d
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid <em>Trypanosoma brucei</em> (Publications)
A whole-organism screen of approximately 87000 compounds against Trypanosoma brucei brucei identified a number of promising compounds for medicinal chemistry optimization. One of these classes of comp
Baseline health conditions in selected communities of northern Sierra Leone as revealed by the health impact assessment of a biofuel project (Publications)
BACKGROUND: As biofuel projects may be associated with positive and negative effects on people's health and wellbeing, a health impact assessment was performed for the Addax Bioenergy Sierra Leone (AB
<em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> genotypes and efficacy of intermittent preventive treatment in Papua New Guinea (Publications)
Intermittent preventive treatment of infants (IPTi) reduces early-childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimala
Exposure to radio-frequency electromagnetic fields from broadcast transmitters and risk of childhood cancer: a census-based cohort study (Publications)
We investigated the association between exposure to radio-frequency electromagnetic fields (RF-EMFs) from broadcast transmitters and childhood cancer. First, we conducted a time-to-event analysis incl