Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized... (Publications)
BACKGROUND: Current World Health Organization (WHO) antiretroviral therapy (ART) guidelines define virologic failure as two consecutive viral load (VL) measurements > /=1,000 copies/mL, triggering emp
Costing malaria interventions from pilots to elimination programmes (Publications)
Background:Malaria programmes in countries with low transmission levels require evidence to optimize deploy-ment of current and new tools to reach elimination with limited resources. Recent pilots of
Developing an SMS text message intervention on sexual and reproductive health with adolescents and youth in Peru (Publications)
BACKGROUND: Improved access to sexual and reproductive health (SRH) services and information is essential for supporting adolescents and youth in making informed decisions and optimizing each young pe
The global progress of soil-transmitted helminthiases control in 2020 and World Health Organization targets for 2030 (Publications)
Soil-transmitted helminth (STH) infections are the most widespread of the neglected tropical diseases, primarily affecting marginalized populations in low- and middle-income countries. More than one b
Clinical data combined with modelling and simulation indicate unchanged drug-drug interaction magnitudes in the elderly (Publications)
Age-related comorbidities and consequently polypharmacy are highly prevalent in the elderly, resulting in an increased risk for drug-drug interactions (DDIs). The effect of aging on DDI magnitudes is
Incidence of depression in relation to transportation noise exposure and noise annoyance in the SAPALDIA study (Publications)
Prospective evidence on the risk of depression in relation to transportation noise exposure and noise annoyance is limited and mixed. We aimed to investigate the associations of long-term exposure to
Informed consent approaches for clinical trial participation of infants with minor parents in sub-Saharan Africa: a systematic review (Publications)
BACKGROUND: Regulations are vague regarding the appropriate decision-maker and authority to consent for children of minor parents participating in clinical trials. In countries with high rates of unde
(+/-)-<em>trans</em>-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: synthesis, <em>in vitro</em> evaluation and SAR analysis (Publications)
Leishmaniasis, a neglected tropical disease caused by parasites of the genus Leishmania, causes a serious burden of disease around the world, represents a threat to the life of millions of people, and
How does district health management emerge within a complex health system? Insights for capacity strengthening in Ghana (Publications)
Introduction: District health managers (DHMs) play a pivotal role in the operation of district health systems in low-and middle income countries, including Ghana. Their capacity is determined by their