Social and cultural aspects of 'malaria' and its control in central Côte d'Ivoire (Publications)
BACKGROUND: A sound local understanding of preventive measures and health-seeking behaviour is important for the effective control of malaria. The purpose of this study was to assess the knowledge, at
HIV infection disrupts the sympatric host-pathogen relationship in human tuberculosis (Publications)
The phylogeographic population structure of Mycobacterium tuberculosis suggests local adaptation to sympatric human populations. We hypothesized that HIV infection, which induces immunodeficiency, wil
Guidance for evidence-informed policies about health systems: rationale for and challenges of guidance development (Publications)
In the first paper in a three-part series on health systems guidance, Xavier Bosch-Capblanch and colleagues examine how guidance is currently formulated in low- and middle-income countries, and the ch
Reduction in the proportion of fevers associated with <em>Plasmodium falciparum</em> parasitaemia in Africa: a systematic review (Publications)
BACKGROUND: Malaria is almost invariably ranked as the leading cause of morbidity and mortality in Africa. There is growing evidence of a decline in malaria transmission, morbidity and mortality over
Contemporary and emerging strategies for eliminating human African trypanosomiasis due to <em>Trypanosoma brucei brucei gambiense</em> (Publications)
OBJECTIVES: To review current and emerging tools for Gambiense HAT control and elimination, and propose strategies that integrate these tools with epidemiological evidence. METHODS: We reviewed the sc
Prodrugs of reverse fosmidomycin analogues (Publications)
Fosmidomycin inhibits IspC (Dxr, 1-deoxy-d-xylulose 5-phosphate reductoisomerase), a key enzyme in nonmevalonate isoprenoid biosynthesis that is essential in Plasmodium falciparum. The drug has been u
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188... (Publications)
BACKGROUND: Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national he
Are well functioning civil registration and vital statistics systems associated with better health outcomes? (Publications)
In this Series paper, we examine whether well functioning civil registration and vital statistics (CRVS) systems are associated with improved population health outcomes. We present a conceptual model
