Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement (Publications)
BACKGROUND: The question of whether air pollution contributes to asthma onset remains unresolved. OBJECTIVES: In this study, we assessed the association between asthma onset in children and traffic-re
Exploring prospects of novel drugs for tuberculosis (Publications)
Tuberculosis remains a disease with an enormous impact on public health worldwide. With the continuously increasing epidemic of drug-resistant tuberculosis, new drugs are desperately needed. However,
Antitrypanosomal sesquiterpene lactones from <em>Saussurea costus</em> (Publications)
In the course of a larger screen of 1800 plant and fungal extracts, the ethyl acetate extract of Saussurea costus roots potently inhibited the growth of Trypanosoma brucei rhodesiense. Subsequent HPLC
Methotrexate and aminopterin lack in vivo antimalarial activity against murine malaria species (Publications)
The antifolate anticancer drug methotrexate (MTX) has potent activity against Plasmodium falciparum in vitro. Experience of its use in the treatment of rheumatoid arthritis indicates that it could be
Longitudinal assessment of <em>Plasmodium falciparum v</em>ar gene transcription in naturally infected asymptomatic children in Papua New Guinea (Publications)
Sequestration and antigenic variation are essential for Plasmodium falciparum survival in vivo contributing to severe pathologic findings and, also, chronic infection. Both are conferred by P. falcipa