Towards a comprehensive simulation model of malaria epidemiology and control (Publications)
SUMMARYPlanning of the control of Plasmodium falciparum malaria leads to a need for models of malaria epidemiology that provide realistic quantitative prediction of likely epidemiological outcomes of a [...] dynamics, limit the applicability of conventional deterministic malaria models. We use individual-based stochastic simulations of malaria epidemiology to predict the impacts of interventions on infection
Prospective risk of morbidity in relation to malaria infection in an area of high endemicity of multiple species of <em>Plasmodium</em> (Publications)
Plasmodium malariae (13.8%), cross-sectional analysis found P. falciparum infection to be independent of the other species despite heterogeneities in transmission. Plasmodium vivax and P. malariae infections [...] health-center morbidity supported the idea that P. malariae infection protects against disease, but indicated greater protection against non-malaria than P. falciparum- associated fevers. Plasmodium vivax [...] infections were negatively correlated. Plasmodium malariae infection was...
Effectiveness of artemether/lumefantrine for the treatment of uncomplicated <em>Plasmodium vivax</em> and <em>P. falciparum</em> malaria in young... (Publications)
uncomplicated Plasmodium falciparum (Pf) malaria, while chloroquine is still widely used for non-Pf infections. A common treatment for both vivax and falciparum malaria would be welcome.Methods. A longitudinal [...] had an infection confirmed by blood slide (BS) examination. Of these, 594 Pv and 332 Pf clinical malaria cases were included in the primary effectiveness analysis. Clinical treatment failure rates at 7 [...] 7, 28 and 42 days were 0.2%, 2.2% and 12.0% for Pv and 0.3%, 1.2% and 3.6%...