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1. Luftqualität, Lungenkrankheiten und öffentliche Gesundheit (Publications)

   Luftqualität, Lungenkrankheiten und öffentliche Gesundheit

   Relevance:

   In den vergangenen Jahren sind die Auswirkungen der heutigen, durch den motorisierten Verkehr und die Industrie verursachten Luftverschmutzung intensiv untersucht worden. Kurzfristig und langfristig e

2. Developmental changes in the circumsporozoite proteins of <em>Plasmodium berghei</em> and <em>P. gallinaceum</em> in their mosquito vectors (Publications)

   Developmental changes in the circumsporozoite proteins of <em>Plasmodium berghei</em> and <em>P. gallinaceum</em> in their mosquito vectors

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3. Treatment of cutaneous leishmaniasis among travellers (Publications)

   Treatment of cutaneous leishmaniasis among travellers

   Relevance:

   Leishmaniasis is endemic in 88 countries on five continents. There are 1-1.5 million cases of cutaneous leishmaniasis reported yearly worldwide. There has been a sharp increase in recorded cases over

4. Novel inhibitors of <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase with anti-malarial activity in the mouse model (Publications)

   Novel inhibitors of <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase with anti-malarial activity in the mouse model

   Relevance:

   Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (

5. Synthesis, structure-activity relationship, and mode-of-action studies of antimalarial reversed chloroquine compounds (Publications)

   Synthesis, structure-activity relationship, and mode-of-action studies of antimalarial reversed chloroquine compounds

   Relevance:

   We have previously shown that a "reversed chloroquine (RCQ)" molecule, composed of a chloroquine-like moiety and a resistance reversal-like moiety, can overcome chloroquine resistance in P. falciparum

6. Shoot growth of mature Fagus sylvatica and Picea abies in relation to ozone (Publications)

   Shoot growth of mature Fagus sylvatica and Picea abies in relation to ozone

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   Epidemiological analysis of sequential growth data may be a tool in assessing ozone sensitivity of mature trees. Annual shoot growth of mature Fagus sylvatica in 83 Swiss permanent forest observation

7. Jozimine A2: the first dimeric dioncophyllaceae-type naphthylisoquinoline alkaloid, with three chiral axes and high antiplasmodial activity (Publications)

   Jozimine A2: the first dimeric dioncophyllaceae-type naphthylisoquinoline alkaloid, with three chiral axes and high antiplasmodial activity

   Relevance:

   A new dimeric naphthylisoquinoline alkaloid, jozimine A(2) (2), was isolated from the root bark of an Ancistrocladus species from the Democratic Republic of Congo. Its absolute stereostructure was det

8. Measuring and validating physical activity and sedentary behavior comparing a parental questionnaire to accelerometer data and diaries (Publications)

   Measuring and validating physical activity and sedentary behavior comparing a parental questionnaire to accelerometer data and diaries

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   Accurately measuring children's physical activity and their sedentary behavior is challenging. The present study compared 189 parental responses to a questionnaire surveying physical activity and sede

9. An alternative form of melarsoprol in sleeping sickness: is an old drug always the best basis for a new one? [Letter] (Publications)

   An alternative form of melarsoprol in sleeping sickness: is an old drug always the best basis for a new one? [Letter]

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10. QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids (Publications)

    QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids

    Relevance:

    Naphthylisoquinoline alkaloids have attracted considerable interest because of their intriguing structure, their unique biosynthetic origin, and their biological activities against several pathogens c