New Modelling Project Launched to Support National Malaria Control Programmes (News)
https://www.swisstph.ch/en/news/new-modelling-project-to-support-national-malaria-control-programmes
application of malaria models, with a focus on the OpenMalaria modelling platform. OpenMalaria is a decision-making tool that was by developed by Swiss TPH to simulate dynamics of malaria transmission and [...] Great achievements have been made in the fight against malaria, saving more than eight million lives and preventing over one-and-a-half billion malaria cases. However, one billion people still live at risk [...] Foundation, to support National Malaria Control Programmes (NMCPs) in their...
New Findings on Malaria Vaccine (News)
https://www.swisstph.ch/en/news/news-detail/news/new-findings-on-malaria-vaccine
with low malaria transmission (Bagomoyo in Tanzania) and two areas with high malaria transmission (Nanoro in Burkina Faso and Kintampo in Ghana). Less effect if children have been exposed to malaria before [...] Carlota Dobaño from ISGlobal. The results also indicate that when a child has already been exposed to malaria (and therefore has anti-CSP antibodies), the protective effect of the vaccine is lower. “This suggests [...] “This research will help to understand the determinants of desired...
Two Decades of Swiss Leadership for New Malaria Medicines (News)
https://www.swisstph.ch/en/news/news-detail/news/two-decades-of-swiss-leadership-for-new-malaria-medicines
for a future without malaria There have been huge strides in the fight against malaria in the last two decades. However, the World Malaria Report 2018 indicates the reduction of malaria cases stalled between [...] fight against malaria remains comprehensive and impactful.” Celebrating achievements and outlook to future Swiss engagement In commemoration of World Malaria Day 2019, SDC and the Swiss Malaria Group (a network [...] research Switzerland has a long history of leadership and engagement...
Analysis of 20 Years Finds Malaria Control in Young Children Saves Lives into Adulthood (News)
https://www.swisstph.ch/en/news/news-detail/news/analysis-of-20-years-finds-malaria-control-in-young-children-saves-lives-into-adulthood
particularly unusual and provides unique insight into the long-term benefits of malaria control in young children. Malaria killed more than 600,000 people in 2020 and is especially dangerous for children [...] bites. In malaria-endemic areas, sleeping under a bed net treated with insecticide is one of the most effective ways to protect young lives. Until now, however, the long-term effect of malaria control in [...] in early childhood has been unclear. Theory suggested that preventing malaria in...
First Malaria Vaccine Recommended for Children by the WHO (News)
https://www.swisstph.ch/en/news/first-malaria-vaccine-recommended-for-children
disease,” said Christian Lengeler, a malaria epidemiologist at Swiss TPH and President of the Swiss Malaria Group. “With a moderate efficacy of 30% of severe malaria cases, the new vaccine still makes a [...] of the five malaria pathogens and the most common in Africa. Swiss TPH has played a leading role in this day coming to fruition thanks to decades of research and development of new malaria vaccines. R [...] RTS,S, produced by GlaxoSmithKline (GSK), belongs to a first generation of malaria...
Accelerated Research and Development Needed to End Malaria (News)
https://www.swisstph.ch/en/news/news-detail/news/accelerated-research-and-development-needed-to-end-malaria
and improve access to services and better surveillance to guide a more targeted malaria response. “To achieve a malaria-free world, we must reinvigorate the drive to find the transformative strategies [...] “Rising to the Challenge of Malaria Eradication” to be held in Geneva on 9 September 2019. Saving lives and boosting economies The findings show that scaling up current malaria interventions would prevent [...] Training for Malaria Control and Elimination. Over the past 3 years, SAGme has...
Malaria Mortality in Africa May Be Higher than Estimated (News)
https://www.swisstph.ch/en/news/news-detail/news/malaria-mortality-in-africa-may-be-higher-than-estimated
confirm that malaria parasite prevalence alone fails to fully capture the association with mortality. The malaria-anaemia comorbidity indicator provides a better measure to estimate the malaria burden." Results [...] number of deaths caused by malaria, different methods and data sources have been utilised. Most studies to date, however, have not taken into account indirect deaths from malaria such as anaemia. Studies [...] Studies also mainly used malaria parasite prevalence as a key measure,...
Changes in Mosquito Behaviour Could Result in Millions of Additional Malaria Cases (News)
https://www.swisstph.ch/en/news/news-detail/news/changes-in-mosquito-behaviour-could-result-in-millions-of-additional-malaria-cases
Countries have substantially reduced the number of malaria cases and deaths since 2000. However, progress has stalled in recent years with an increase in malaria cases and deaths reported in sub-Saharan Africa [...] vector control interventions to prevent malaria transmission, however, they primarily protect against mosquito bites when people are indoors. 12 million additional malaria cases to be expected A new study found [...] London, the University of Surrey, the U.S. President's Malaria...
Evaluation of malaria rapid diagnostic test performance and <em>pfhrp2</em> deletion in Tanzania school surveys, 2017 (Publications)
As part of malaria nationwide monitoring and evaluation initiatives, there is an increasing trend of incorporating malaria rapid diagnostic tests (mRDTs) in surveys conducted within primary schools to [...] to detect malaria parasites. However, mRDTs based on the detection of histidine-rich protein 2 (HRP2) are known to yield false-positive results due to persistent antigenemia, and false-negative results may
Design and selection of drug properties to increase the public health impact of next-generation seasonal malaria chemoprevention: a modelling study (Publications)
BACKGROUND: Seasonal malaria chemoprevention (SMC) is recommended for disease control in settings with moderate to high Plasmodium falciparum transmission and currently depends on the administration of [...] threaten the effectiveness of SMC. Guidance is needed to de-risk the development of drug compounds for malaria prevention. We aimed to provide guidance for the early prioritisation of new and alternative SMC [...] their target product profiles. METHODS: In this modelling study, we combined...
