Rapid and accurate detection of <em>Mycobacterium tuberculosis</em> in sputum samples by Cepheid Xpert MTB/RIF assay - a clinical validation study (Publications)
BACKGROUND: A crucial impediment to global tuberculosis control is the lack of an accurate, rapid diagnostic test for detection of patients with active TB. A new, rapid diagnostic method, (Cepheid) Xp
Comparison of <em>Plasmodium falciparum</em> allelic frequency distribution in different endemic settings by high-resolution genotyping (Publications)
BACKGROUND: The diversity of genotyping markers of Plasmodium falciparum depends on transmission intensity. It has been reported that the diversity of the merozoite surface protein 2 (msp2) is greater
Modelling age-heterogeneous <em>Schistosoma haematobium</em> and <em>S. mansoni</em> survey data via alignment factors (Publications)
ABSTRACT: BACKGROUND: Reliable maps of the geographical distribution, number of infected individuals and burden estimates of schistosomiasis are essential tools to plan, monitor and evaluate control p
Costs of illness due to cholera, costs of immunization and cost-effectiveness of an oral cholera mass vaccination campaign in Zanzibar (Publications)
BACKGROUND: The World Health Organization (WHO) recommends oral cholera vaccines (OCVs) as a supplementary tool to conventional prevention of cholera. Dukoral, a killed whole-cell two-dose OCV, was us
Simulation of the cost-effectiveness of malaria vaccines (Publications)
BACKGROUND: A wide range of possible malaria vaccines is being considered and there is a need to identify which vaccines should be prioritized for clinical development. An important element of the inf
Improved protective efficacy of a species-specific DNA vaccine encoding mycolyl-transferase Ag85A from <em>Mycobacterium ulcerans</em> by homologous... (Publications)
Vaccination with plasmid DNA encoding Ag85A from M. bovis BCG can partially protect C57BL/6 mice against a subsequent footpad challenge with M. ulcerans. Unfortunately, this cross-reactive protection
Specificity of human immunodeficiency virus (LAV/HTLV-III)-reactive antibodies in African sera from southeastern Tanzania (Publications)
The prevalence of antibodies to human immunodeficiency virus (HIV = LAV/HTLV-III) in a rural population from the Ifakara area in southeastern Tanzania was investigated. Sera from 286 individuals colle
Laboratory and field trials at Ifakara (Kilombero District, Tanzania) on the plant molluscicide <em>Swartzia madagascariensis</em> (Publications)
The molluscicidal activity of crushed seed pods of Swartzia madagascariensis was assessed by laboratory and field trials. Mature dry seed pods were ground and extracted in tap water for 24 h. Water ex
