hERG,<em> Plasmodium</em> life cycle, and cross resistance profiling of new azabenzimidazole analogues of astemizole (Publications)
Toward addressing the cardiotoxicity liability associated with the antimalarial drug astemizole (AST, hERG IC50 = 0.0042 μM) and its derivatives, we designed and synthesized analogues based on compoun
A new model for ranking schools of public health: the public health academic ranking (Publications)
Objectives: As there is no ranking designed for schools of Public Health, the aim of this project was to create one. Methods: To design the Public Health Academic Ranking (PHAR), we used the InCites B
Phylogenetic analysis of pyruvate-ferredoxin oxidoreductase, a redox enzyme involved in the pharmacological activation of nitro-based prodrugs in... (Publications)
The present frontrunners in the chemotherapy of infections caused by protozoa are nitro-based prodrugs that are selectively activated by PFOR-mediated redox reactions. This study seeks to analyze the
Child health and infection with low density (CHILD) malaria: a protocol for a randomised controlled trial to assess the long-term health and... (Publications)
INTRODUCTION: As malaria declines, low-density malaria infections (LMIs) represent an increasing proportion of infections and may have negative impacts on child health and cognition, necessitating dev
Non-communicable disease care in Sierra Leone: a mixed-methods study of the drivers and barriers to retention in care for hypertension (Publications)
OBJECTIVE: To retrospectively analyse routinely collected data on the drivers and barriers to retention in chronic care for patients with hypertension in the Kono District of Sierra Leone. DESIGN: Con
Antiparasitic stewardship: a call to action (Publications)
There is an urgent need to consider antiparasitic drugs in global efforts to achieve and implement equitable and sustainable antimicrobial stewardship initiatives worldwide.
Engaging men in women's empowerment: impact of a complex gender transformative intervention on household socio-economic and health outcomes in the... (Publications)
BACKGROUND: In the Democratic Republic of the Congo, women in (peri-)urban areas are commonly engaged in small trade, which allows them to meet the basic needs of their families. Microsaving approache
A 24-week, all-oral regimen for rifampin-resistant tuberculosis (Publications)
BACKGROUND: In patients with rifampin-resistant tuberculosis, all-oral treatment regimens that are more effective, shorter, and have a more acceptable side-effect profile than current regimens are nee
From diversity to uniformity: comparing nutritional transition of food consumption in four regions in Senegal (Publications)
Rapid changes in the social and economic environment in the last few decades have resulted in a nutrition transition observed in many African countries, revealing large shifts in diet. Central to this
