Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination (Publications)
During the SARS-CoV-2 pandemic, novel and traditional vaccine strategies have been deployed globally. We investigated whether antibodies stimulated by mRNA vaccination (BNT162b2), including third-dose
Reinfection with SARS-CoV-2 and waning humoral immunity: a case report (Publications)
Recovery from COVID-19 is associated with production of anti-SARS-CoV-2 antibodies, but it is uncertain whether these confer immunity. We describe viral RNA shedding duration in hospitalized patients
Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8(+) T cell responses post SARS-CoV-2 infection (Publications)
T cells are a critical component of the response to SARS-CoV-2, but their kinetics after infection and vaccination are insufficiently understood. Using "spheromer" peptide-MHC multimer reagents, we an
Development of a hookworm egg hatching assay to determine the ovicidal effects of anthelminthics (Publications)
BACKGROUND: Few anthelminthics are currently available, manifesting the urgent need for new treatment options. In vitro profiling of current anthelminthics against larval and adult stage helminths dis
Adoption of mHealth technologies by community health workers to improve the use of maternal health services in sub-Saharan Africa: protocol for a... (Publications)
BACKGROUND: Studies have shown that mobile health technologies (mHealth) enhance the use of maternal health services. However, there is limited evidence of the impact of mHealth use by community healt
CALINA Study Shows Positive Efficacy and Safety Data for a Novel Treatment for Small Babies (News)
https://www.swisstph.ch/en/news/news-detail/news/calina-study-shows-positive-efficacy-and-safety-data-for-a-novel-treatment-for-babies
Malaria exerts a massive burden on public health across the world, particularly in Africa. Huge strides have been made in recent decades in the treatment of malaria. However, to date, little data has
Accelerating the Fight against Malaria - World Malaria Day 2024 (News)
https://www.swisstph.ch/en/news/accelerating-the-fight-against-malaria-world-malaria-day-2024
In the last few years, efforts to curb malaria have unfortunately been stalling. In 2022, over 600,000 people died from malaria, primarily children under the age of 5 in sub-Saharan Africa. People liv
New Discovery Unravels Malaria Invasion Mechanism (News)
https://www.swisstph.ch/en/news/news-detail/news/new-discovery-unravels-malaria-invasion-mechanism
With 249 million cases of malaria and 608,000 deaths in 2022, malaria has remained an intractable global health threat. The malaria parasite Plasmodium falciparum is the leading cause of severe malari
Parasitic Worms and Liver Disease in Rural Laos (News)
https://www.swisstph.ch/en/news/parasitic-worms-and-liver-disease-in-rural-laos
Shedding light on the SLD prevalence Steatotic Liver Disease (SLD), also known as fatty liver disease, is a condition characterised by the accumulation of fat in the liver cells. SLD normally does not
Temperature-mortality associations by age and cause: a multi-country multi-city study (Publications)
BACKGROUND: Heterogeneity in temperature-mortality relationships across locations may partly result from differences in the demographic structure of populations and their cause-specific vulnerabilitie
