Searched for malaria.

1. QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids (Publications)

   QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids

   Relevance:

   pharmacologic properties make them suitable lead structures for new agents, in particular against malaria. Since these natural products are not easy to isolate in sufficient quantities or to synthesize

2. The pharmacokinetics and drug-drug interactions of ivermectin in <em>Aedes aegypti</em> mosquitoes (Publications)

   The pharmacokinetics and drug-drug interactions of ivermectin in <em>Aedes aegypti</em> mosquitoes

   Relevance:

   Mosquitoes are vectors of major diseases such as dengue fever and malaria. Mass drug administration of endectocides to humans and livestock is a promising complementary approach to current insecticide-based

3. Spatial epidemiology in zoonotic parasitic diseases: insights gained at the 1st International Symposium on Geospatial Health in Lijiang, China, 2007 (Publications)

   Spatial epidemiology in zoonotic parasitic diseases: insights gained at the 1st International Symposium on Geospatial Health in Lijiang, China, 2007

   Relevance:

   and water-borne helminth infections, as well as arthropod-borne diseases such as leishmaniasis, malaria and lymphatic filariasis. The work made public at this occasion is briefly summarized here to highlight

4. Repurposing know-how for drug development: case studies from the Swiss Tropical and Public Health Institute (Publications)

   Repurposing know-how for drug development: case studies from the Swiss Tropical and Public Health Institute

   Relevance:

   of neglected tropical diseases and other infectious diseases of poverty, such as schistosomiasis, malaria and human African trypanosomiasis.

5. Master of Science in Infection Biology | Swiss TPH (Page)

   Master of Science in Infection Biology | Swiss TPH

   Relevance:
   https://www.swisstph.ch/en/study-with-us/bachelor-and-master/msc-in-infection-biology

   early male gametocyte-specific protein which can help us further understand transmission stages of malaria. With half the world's population at risk of becoming infected, basic research into the intricate [...] intricate biology of the parasite is crucial.” Patricia Landeau Millan MSc Infection Biology student, Malaria Gene Regulation Unit At a Glance Duration: 3 semesters (90 ECTS) starting from September (Autumn semester)

6. Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3 deletions in <em>Plasmodium falciparum</em>... (Publications)

   Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3 deletions in <em>Plasmodium falciparum</em> infections from Rukara, Rwanda

   Relevance:

   BACKGROUND: Emerging artemisinin partial resistance and diagnostic resistance are a threat to malaria control in Africa. Plasmodium falciparum kelch13 (k13) propeller-domain mutations that confer artemisinin [...] provide early detection of partner drug resistance, which would likely compromise control and increase malaria morbidity and mortality in East Africa.

7. Adherence to prescribed artemisinin-based combination therapy in Garissa and Bunyala districts, Kenya (Publications)

   Adherence to prescribed artemisinin-based combination therapy in Garissa and Bunyala districts, Kenya

   Relevance:

   anti-malarial mono-therapies, malaria endemic countries in Africa now use artemisinin-based combination therapy (ACT) as recommended first-line treatment for uncomplicated malaria. Patients' adherence to ACT

8. Sub-lethal exposure to chlorfenapyr reduces the probability of developing <em>Plasmodium falciparum</em> parasites in surviving Anopheles mosquitoes (Publications)

   Sub-lethal exposure to chlorfenapyr reduces the probability of developing <em>Plasmodium falciparum</em> parasites in surviving Anopheles mosquitoes

   Relevance:

   BACKGROUND: Pyrethroid resistance in the key malaria vectors threatens the success of pyrethroid-treated nets. To overcome pyrethroid resistance, Interceptor(®) G2 (IG2), a 'first-in-class' dual insecticidal [...] the intensity of the P. falciparum infection. This will likely also contribute to the reduction of malaria in communities beyond the direct killing of mosquitoes.

9. Multi-country evaluation of the durability of pyrethroid plus piperonyl-butoxide insecticide-treated nets: study protocol (Publications)

   Multi-country evaluation of the durability of pyrethroid plus piperonyl-butoxide insecticide-treated nets: study protocol

   Relevance:

   distributions of long-lasting insecticidal nets (LLINs) have contributed to large reductions in the malaria burden. However, this success is in jeopardy due in part to the increasing pyrethroid-resistant mosquito [...] containing pyrethroid and piperonyl-butoxide (PBO) have shown a greater reduction in the incidence of malaria than pyrethroid LLINs in areas with pyrethroid-resistant mosquitoes. However, the durability (attrition

10. Incidence and consequences of damage to insecticide-treated mosquito nets in Kenya (Publications)

    Incidence and consequences of damage to insecticide-treated mosquito nets in Kenya

    Relevance:

    estimated to account for 7-11% of loss in effect on vectorial capacity for Plasmodium falciparum malaria in an analysis of repeated cross-sectional surveys of LLINs in Kenya. This does not account for the [...] nets could substantially increase their lifetime and impact but the impact of LLIN programmes on malaria transmission is ultimately limited by levels of use. Longitudinal analyses of net integrity data