Pharmacokinetics of ivermectin metabolites and their activity against <em>Anopheles stephensi </em>mosquitoes (Publications)
treat worm infections and ectoparasites including lice and scabies mites. Furthermore, survival of malaria transmitting Anopheles mosquitoes is strongly decreased after feeding on humans recently treated [...] . Currently, mass drug administration of ivermectin is under investigation as a potential novel malaria vector control tool to reduce Plasmodium transmission by mosquitoes. A "post-ivermectin effect" has
Relationship between insecticide resistance profiles in <em>Anopheles gambiae</em> <em>sensu lato</em> and agricultural practices in Côte... (Publications)
BACKGROUND: Insecticide-based malaria vector control is increasingly undermined due to the development of insecticide resistance in mosquitoes. Insecticide resistance may partially be related to the use [...] s between the type of agricultural practices and certain insecticide resistance profiles in the malaria vector An. gambiae s.l. which might arise from the use of pesticides deployed for protecting crops
Significant geographical differences in prevalence of mutations associated with <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> drug... (Publications)
resistance remains a major obstacle to malaria treatment and control. It can arise and spread rapidly, and vary substantially even at sub-national level. National malaria programmes require cost-effective and
Gene Coverage Count and Classification (GC3): a locus sequence coverage assessment tool using short-read whole genome sequencing data, and its... (Publications)
BACKGROUND: The ability of malaria rapid diagnostic tests (RDTs) to effectively detect active infections is being compromised by the presence of malaria strains with genomic deletions at the hrp2 and hrp3
Significant geographical differences in prevalence of mutations associated with <em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> drug... (Publications)
resistance remains a major obstacle to malaria treatment and control. It can arise and spread rapidly, and vary substantially even at sub-national level. National malaria programmes require cost-effective and
The <em>Plasmodium falciparum</em> histone methyltransferase PfSET10 is dispensable for the regulation of antigenic variation and gene expression in... (Publications)
The malaria parasite Plasmodium falciparum employs antigenic variation of the virulence factor P. falciparum erythrocyte membrane protein 1 (PfEMP1) to escape adaptive immune responses during blood infection [...] for life cycle progression in the mosquito vector or during liver stage development.IMPORTANCEThe malaria parasite Plasmodium falciparum infects hundreds of millions of people every year. To survive and
R. Geigy Award 2024: Cutting-Edge Research to Control Communicable and Non-Communicable Diseases in Côte D’Ivoire (News)
https://www.swisstph.ch/en/news/news-detail/news/r-geigy-award-2024-cutting-edge-research-to-control-communicable-and-non-communicable-diseases-in-cote-divoire
Department at Swiss TPH and Member of the Board at the R. Geigy-Foundation. New insecticides to control malaria and dengue fever The research work of Julien Zahouli, Emmanuelle Lisro, Laurence Yao and Marc Adou [...] insecticides to combat disease-transmitting mosquitoes such as Anopheles gambiae (vector of the malaria parasite) and Aedes aegypti (vector of the dengue virus). “Julien Zahouli, Emmanuelle Lisro, Laurence
New Understanding of Childhood Immune Systems May Improve Vaccine Efficacy (News)
https://www.swisstph.ch/en/news/news-detail/news/new-understanding-of-childhood-immune-systems-may-improve-vaccine-efficacy
months from infants and children living in Tanzania and Mozambique as part of the phase III RTS,S malaria vaccine trial. Groups of children that responded with better antibody titers to the RTS,S vaccine [...] Despite the success rates of childhood immunization, there are still many infectious diseases, such as malaria, that require vaccination-based interventions. It is likely that such solutions will come from a
Relationship between insecticide resistance profiles in <em>Anopheles gambiae</em> <em>sensu lato</em> and agricultural practices in Côte... (Publications)
BACKGROUND: Insecticide-based malaria vector control is increasingly undermined due to the development of insecticide resistance in mosquitoes. Insecticide resistance may partially be related to the use [...] s between the type of agricultural practices and certain insecticide resistance profiles in the malaria vector An. gambiae s.l. which might arise from the use of pesticides deployed for protecting crops
Pharmacokinetics of ivermectin metabolites and their activity against <em>Anopheles stephensi </em>mosquitoes (Publications)
treat worm infections and ectoparasites including lice and scabies mites. Furthermore, survival of malaria transmitting Anopheles mosquitoes is strongly decreased after feeding on humans recently treated [...] . Currently, mass drug administration of ivermectin is under investigation as a potential novel malaria vector control tool to reduce Plasmodium transmission by mosquitoes. A "post-ivermectin effect" has
