Searched for malaria.

1. Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5'-carboxamidoadenosine analogues (Publications)

   Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5'-carboxamidoadenosine analogues

   Relevance:

   rapid increase of resistance to drugs commonly used in the treatment of tropical diseases such as malaria and African sleeping sickness calls for the prompt development of new safe and efficacious drugs

2. Alterations in local chromatin environment are involved in silencing and activation of subtelomeric var genes in <em>Plasmodium falciparum</em> (Publications)

   Alterations in local chromatin environment are involved in silencing and activation of subtelomeric var genes in <em>Plasmodium falciparum</em>

   Relevance:

   family, undergoes antigenic variation and plays an important role in chronic infection and severe malaria. Only a single var gene is transcribed per parasite, and epigenetic control mechanisms are fundamental

3. Field evaluation of spatial repellency of metofluthrin-impregnated plastic strips against <em>Anopheles gambiae</em> complex in Bagamoyo, coastal... (Publications)

   Field evaluation of spatial repellency of metofluthrin-impregnated plastic strips against <em>Anopheles gambiae</em> complex in Bagamoyo, coastal Tanzania

   Relevance:

   study reports the efficacy of the new prototypes of metofluthrin-impregnated plastic strips against malaria vectors, Anopheles gambiae complex, in the Kongo villages of Bagamoyo district in coastal Tanzania

4. Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from <em>Plasmodium falciparum</em> merozoite surface... (Publications)

   Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from <em>Plasmodium falciparum</em> merozoite surface protein-1

   Relevance:

   iented approach to the study and optimization of the antigenicity of the protein as a potential malaria vaccine candidate, whilst exploiting the immunopotentiating properties of influenza virosomes as

5. Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese... (Publications)

   Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese <em>Ancistrocladus</em> plant

   Relevance:

   potent growth-inhibitory activity against Plasmodium falciparum, the protozoal pathogen causing malaria, and moderate effects on Trypanosoma brucei rhodesiense, the parasite responsible for African sleeping

6. Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on... (Publications)

   Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on mepacrine-conjugated diaryl sulfide scaffolds

   Relevance:

   sub-micromolar range against Trypanosoma brucei rhodesiense and Trypanosoma cruzi, as well as the malaria parasite Plasmodium falciparum, which lack trypanothione metabolism. The inhibitors exhibit strong

7. Antiprotozoal activities of traditional medicinal plants from the Garhwal region of North West Himalaya, India (Publications)

   Antiprotozoal activities of traditional medicinal plants from the Garhwal region of North West Himalaya, India

   Relevance:

   Garhwal region of North West Himalaya for the treatment of protozoal infections and fever including malaria. MATERIALS AND METHODS: In vitro activity against erythrocytic stages of Plasmodium falciparum was

8. Antigenic cross-reactivity between different alleles of the <em>Plasmodium falciparum </em>merozoite surface protein 2 (Publications)

   Antigenic cross-reactivity between different alleles of the <em>Plasmodium falciparum </em>merozoite surface protein 2

   Relevance:

   encoding Plasmodium falciparum merozoite surface protein 2 (MSP2) was PCR amplified from blood of malaria patients, genotyped, and 19 distinct fragments were cloned and expressed in E. coli. The reactivity

9. Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa (Publications)

   Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa

   Relevance:

   lessons from the mapping of human helminth infections may also be relevant for the rapid mapping of malaria as its control efforts are intensified

10. Complete structural assignment of serratol, a cembrane-type diterpene from <em>Boswellia serrata</em>, and evaluation of its antiprotozoal activity (Publications)

    Complete structural assignment of serratol, a cembrane-type diterpene from <em>Boswellia serrata</em>, and evaluation of its antiprotozoal activity

    Relevance:

    T. cruzi (Chagas' disease), Leishmania donovani (Kala-Azar), and Plasmodium falciparum (Tropical Malaria). It was found active against T. brucei and P. falciparum. These activities were 10- to 15-fold higher