Estimation of infection and recovery rates for highly polymorphic parasites when detectability is imperfect, using hidden Markov models (Publications)
implemented using Markov chain Monte Carlo simulation. The model is applied to a panel data set of malaria genotype data from a randomized controlled trial of bed nets in Tanzanian children aged 6-30 months
Naomi Chi Ndum (People)
https://www.swisstph.ch/en/staff/profile/people/naomi-chi-ndum
training. She has clinical and field epidemiology experience in managing tropical diseases like malaria, schistosomiasis, helthminthiasis and most other NTDs in hard to reach areas. Naomi has a strong
Monica Golumbeanu (People)
https://www.swisstph.ch/en/staff/profile/people/monica-golumbeanu
her research focuses on developing data-driven computational analyses and mathematical models of malaria infection dynamics to assess the impact of interventions on host and parasite populations. Previously
Günther Fink (People)
https://www.swisstph.ch/en/staff/profile/people/guenther-fink
programs in Nigeria, and large-scale private and public sector initiatives to reduce the burden of malaria in Angola, Namibia, Uganda and Zambia. He is the PI of the Zambia Early Childhood Development Project
Systems Performance and Monitoring (Page)
https://www.swisstph.ch/en/about/scih/systems-performance-and-monitoring
AIDS, Tuberculosis and Malaria created in 2002 to significantly increase resources to fight the three of the world's most devastating diseases (HIV and AIDS, Tuberculosis, and Malaria), and to direct those [...] adults. Am J Trop Med Hyg . 2023;109(1):138-146. DOI: 10.4269/ajtmh.22-0773 Related Topics HIV / AIDS Malaria Neglected Tropical Diseases (NTDs) Tuberculosis Related Activities Consultancy and Policy Advice
Vector Biology | Research at Swiss TPH (Page)
https://www.swisstph.ch/en/about/eph/vector-biology
particularly important vectors as they spread some of the most devastating infectious diseases such as malaria, dengue fever, West Nile fever or Zika virus infections. Investigation of Vectors and Development
<em>In vitro</em> assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of <em>Plasmodium falciparum</em> (Publications)
OBJECTIVES: Using synchronous cultures of Plasmodium falciparum malaria, the stage sensitivity of the parasite to OZ277 (RBx-11160), the first fully synthetic antimalarial peroxide that has entered Phase
Probing the antimalarial mechanism of artemisinin and OZ277 (arterolane) with nonperoxidic isosteres and nitroxyl radicals (Publications)
such as the semisynthetic artemisinins are critically important in the treatment of drug-resistant malaria. Nevertheless, their peroxide bond-dependent mode of action is still not well understood. Using
Insecticide susceptibility of <em>Anopheles </em>mosquitoes changes in response to variations in the larval environment (Publications)
Insecticide resistance threatens the success achieved through vector control in reducing the burden of malaria. An understanding of insecticide resistance mechanisms would help to develop novel tools and strategies
Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds (Publications)
moiety, demonstrated in vivo antiplasmodial activity after oral administration in a P. berghei malaria model, although no complete parasite elimination was achieved with a four-dose regimen. The in vivo
