Alterations in T cell subsets in human immunodeficiency virus-infected adults with co-infections in southern Mozambique (Publications)
viruses I and II [HTLV-I/II], Kaposi sarcoma-associated herpesvirus [KSHV], Plasmodium falciparum malaria, and tuberculosis), and levels of activated CD8 and CD4 T cell subsets as well as naive and memory
Morbidity due to <em>Schistosoma mansoni</em>: an epidemiological assessment of distended abdomen syndrome in Ugandan school children with... (Publications)
chronically evolved morbidity and/or that other interacting factors were involved, e.g. malnutrition and malaria. At 1-year follow-up, ACR scores showed an overall trend of regression towards the mean, potentially
Fiona Vanobberghen (People)
https://www.swisstph.ch/en/staff/profile/people/fiona-vanobberghen
on Design and analysis of pharmacokinetic and pharmacodynamic (PK/PD) studies for helminths and malaria In addition, my experience and interests span HIV epidemiology and clinical trials, the use of marginal
Micronutrient status, food security, anaemia, <em>Plasmodium</em> infection, and physical activity as predictors of primary schoolchildren's body... (Publications)
increased MVPA was associated with reduced fat mass among girls. CONCLUSIONS: The integration of Malaria control programs with efforts to improve household healthy diet and promote physical activity can
Key contributions by the Swiss Tropical and Public Health Institute towards new and better drugs for tropical diseases (Publications)
clonorchiasis, fascioliasis and opisthorchiasis), human African trypanosomiasis, leishmaniasis, malaria, schistosomiasis, soil-transmitted helminthiasis and tuberculosis. In this article, we show case
Chemoproteomics validates selective targeting of <em>Plasmodium</em> M1 alanyl aminopeptidase as an antimalarial strategy (Publications)
New antimalarial drug candidates that act via novel mechanisms are urgently needed to combat malaria drug resistance. Here, we describe the multi-omic chemical validation of Plasmodium M1 alanyl metal
The cost-effectiveness of permethrin impregnated bednets in preventing child mortality in Kassena-Nankana district of Northern Ghana (Publications)
bednets are now being widely promoted as an effective means of protecting African children against malaria, but there is little evidence of their cost-effectiveness. The impact on child mortality of introducing
Neglected Tropical Diseases: Then and Now (Page)
https://www.swisstph.ch/en/impact-stories/neglected-tropical-diseases-then-and-now
MDGs were health-related, focusing on child and maternal health as well as on combatting “HIV/AIDS, malaria, and other diseases”. The MDG era spurred an unprecedented global health effort, facilitated by a [...] Global Fund, and the creation of product development partnerships (PDPs), such as Medicines for Malaria Venture (MMV), FIND and Drugs for Neglected Diseases initiative (DND i ). The Birth of the Term [...] initial group of 13 to 15 NTDs was similar to that of any of the ‘big three’...
Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: antimicrobial evaluation and mechanistic insights (Publications)
activity against the chloroquine-sensitive NF54 and multi-drug resistant K1 strains of the human malaria parasite, Plasmodium falciparum. All compounds were active against the two strains, generally showing
Immune system development varies according to age, location, and anemia in African children (Publications)
Mozambique by detailed immunophenotyping of longitudinal blood samples collected during the RTS,S malaria vaccine phase 3 trial. In these cohorts, the composition of the immune system is dynamically transformed
