Analysis of <em>Plasmodium falciparum</em> infections in a village community in Northern Nigeria: determination of msp2 genotypes and parasitespecific... (Publications)
PNG. The prevalence of IgG antibodies against the circumsporozoite protein (CSP), an indicator for malaria exposure, was over 85% in all age groups showing a high exposure of villagers to P. falciparum. OD
In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in <em>Plasmodium... (Publications)
artemisinin-based combination therapy (ACT) recommended as first-line treatment of Plasmodium falciparum malaria in disease-endemic countries. Studies by Eckstein-Ludwig and co-workers showed both thapsigargin
Global metabolic responses of NMRI mice to an experimental <em>Plasmodium berghei</em> infection (Publications)
metabolic profiling may provide a sensitive diagnostic tool of Plasmodium infection and the control of malaria more generally
Evidence for limited activation of distinct CD4+ T cell subsets in response to the <em>Plasmodium falciparum </em>circumsporozoite protein in Papua... (Publications)
In this study, we have studied cellular and humoral responses of individuals naturally exposed to malaria in a highly endemic region of Papua New Guinea to the circumsporozoite protein of Plasmodium falciparum
Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant <em>Plasmodium falciparum</em>... (Publications)
Plasmodium falciparum, the most deadly malaria agent, displays a wide variety of resistance mechanisms in the field. The ability of antimalarial compounds in development to overcome these must therefore
The epidemiology of multiple <em>Plasmodium falciparum</em> infections. 9. Effect of insecticide-treated bed nets on haemoglobin values, prevalence... (Publications)
randomized controlled trial of insecticide-treated bed nets (ITNs) was conducted in an area of high malaria transmission in Tanzania in order to assess the effects of ITNs on infection and anaemia. One hundred
More than seven decades of <em>Acta Tropica</em>: looking back to move into the future (Publications)
surveillance, control, and elimination of diseases that are intimately linked to poverty, such as malaria and neglected tropical diseases. In recent years, the scope of Acta Tropica was widening to target
Time to scale up molecular surveillance for anti-malarial drug resistance in sub-Saharan Africa (Publications)
emergence of resistance. However, molecular markers are not monitored systematically by national malaria control programmes, and are often assessed in research studies, but not in routine surveillance.
Novel inhibitors of <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase with anti-malarial activity in the mouse model (Publications)
Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (DHODH)
Variation in calculating and reporting antimalarial efficacy against<em> Plasmodium falciparum</em> in sub-Saharan Africa: a systematic review of... (Publications)
artemisinin-based combination therapies (ACTs), are critical tools in reducing the global burden of malaria, which is concentrated in sub-Saharan Africa. Performing and reporting antimalarial efficacy studies
