Passive immunoprotection of <em>Plasmodium falciparum</em>-infected mice designates the CyRPA as candidate malaria vaccine antigen (Publications)
malaria. In an endeavor to identify novel vaccine targets, we tested predicted Plasmodium falciparum open reading frames for proteins that elicit parasite-inhibitory Abs. This has led to the identification
Reinvestigation of the <em>Saccharomyces cerevisiae</em> genome annotation by comparison to the genome of a related fungus: <em>Ashbya gossypii</em> (Publications)
syntenic regions leading to an improved annotation. RESULTS: We have identified 23 novel S. cerevisiae open reading frames (ORFs) as syntenic homologs of A. gossypii genes; for all but one, homologs are present
Connecting the Dots. Teaching, Research and Services in the Great Lakes Region (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/connecting-the-dots-teaching-research-and-services-in-the-great-lakes-region
Research and Services in the Great Lakes Region” was to complement the portfolio of the Swiss TPH office opened in Bukavu with a strong capacity building component in implementation research of young researchers
Spatial analysis of schistosomiasis in Hunan and Jiangxi provinces in the People's Republic of China (Publications)
in Hunan, indicating that schistosomiasis control should target individuals in close proximity to open water sources as they are at highest risk of infection.
Tuberculosis mortality and living conditions in Bern, Switzerland, 1856-1950 (Publications)
in 1856 to 33 per 100,000 in 1950, as housing conditions improved, indoor crowding decreased, and open-air schools, sanatoria, systematic tuberculin skin testing of school children and chest radiography
Collaborating with Complementary and Alternative Medicine (CAM) providers when writing HPV vaccine review articles (Publications)
important to VH HCPs. Contrary to our initial expectations, and in an inclusive, respectful atmosphere of open dialogue, we were able to productively finalize our manuscripts. In the opinion of the CAM co-authors
Epidemiologie, Klinik, Diagnostik und Therapie von Infektionen durch <em>Mycobacterium chimaera</em> (Publications)
increasingly reported over the past few years. Most infections occurred in patients who had undergone open-chest cardiothoracic surgery. Epidemiological and molecular studies showed that transmission of M
Modeling indoor air pollution of outdoor origin in homes of SAPALDIA subjects in Switzerland (Publications)
indoors were between 30% and 66%, the highest one was observed for PMabsorbance. A modifying effect of open windows was found for NO2 and the ultrafine particle number concentration. Cooking was associated
Short course amphotericin B in addition to sertraline and fluconazole for treatment of HIV-associated cryptococcal meningitis in rural Tanzania (Publications)
activity against Cryptococcus and bi-directional synergy with fluconazole. METHODS: We conducted an open label clinical trial to assess the safety and efficacy of sertraline 400 mg/day and fluconazole 1200
Integrating standardized whole genome sequence analysis with a global <em>Mycobacterium tuberculosis</em> antibiotic resistance knowledgebase (Publications)
from MTBC sequence data. Stringent thresholds and quality control measures were incorporated in this open source tool. The pipeline was validated using a well-characterized dataset of 90 diverse MTBC isolates
