A qualitative appraisal of stakeholder reactions to a tool for burden of disease-based health system budgeting in Ghana (Publications)
were drawn from the national, regional, and district levels of the health system and interviewed in open-ended discussions about their reactions to DiHPART and suggestions for systems development. RESULTS:
Assessing the relationship between environmental factors and malaria vector breeding sites in Swaziland using multi-scale remotely sensed data (Publications)
with high spatial resolution has often resulted in analyses being conducted at coarse scales using open-source, archived remotely sensed data. In the present study, spatial prediction of potential breeding
Functional characterization and phenotypic monitoring of human hematopoietic stem cell expansion and differentiation of monocytes and macrophages by... (Publications)
e blood monocytes-derived from HSC-derived macrophages. To conclude, we propose that this method opens new avenues to distinguish the impact of human genetics on the dysregulated biological properties
wIRA: hyperthermia as a treatment option for intracellular bacteria, with special focus on Chlamydiae and Mycobacteria (Publications)
infections are presented. Finally, technical aspects of using wIRA in patients are critically reviewed and open questions driving future research are highlighted. In conclusion, wIRA is a promising tool for reducing
Quantification of self pollution from two diesel school buses using three independent methods (Publications)
balance (CMB) methods. Each bus drove along a residential route simulating stops, with windows closed or open. Particulate matter (PM) and its constituents were monitored in the bus and from a LV. We collected
Reinvestigation of the <em>Saccharomyces cerevisiae</em> genome annotation by comparison to the genome of a related fungus: <em>Ashbya gossypii</em> (Publications)
syntenic regions leading to an improved annotation. RESULTS: We have identified 23 novel S. cerevisiae open reading frames (ORFs) as syntenic homologs of A. gossypii genes; for all but one, homologs are present
Isothermal microcalorimetry accurately detects bacteria, tumorous microtissues, and parasitic worms in a label-free well-plate assay (Publications)
monitored and corresponds to a diameter increase of the microtissues from ca 100 to 428mum. This opens new research avenues in cancer research, diagnostics and development of new antitumor drugs. For parasitic
Passive immunoprotection of <em>Plasmodium falciparum</em>-infected mice designates the CyRPA as candidate malaria vaccine antigen (Publications)
malaria. In an endeavor to identify novel vaccine targets, we tested predicted Plasmodium falciparum open reading frames for proteins that elicit parasite-inhibitory Abs. This has led to the identification
Developing the building blocks to elucidate the impact of the urban exposome on cardiometabolic-pulmonary disease: the EU EXPANSE project (Publications)
EXPANSE will translate its insights and innovations into research and dissemination tools that will be openly accessible via the EXPANSE toolbox. By applying innovative ethics-by-design throughout the project
CNS immune privilege: hiding in plain sight (Publications)
ability to direct neuroprotective lymphocyte responses. This newer view of CNS immune privilege is opening the door for therapies designed to harness autoreactive lymphocyte responses and also implies (i)