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1. Efficacy and safety of pafuramidine versus pentamidine maleate for treatment of first stage sleeping sickness in a randomized, comparator-controlled,... (Publications)

   Efficacy and safety of pafuramidine versus pentamidine maleate for treatment of first stage sleeping sickness in a randomized, comparator-controlled, international phase 3 clinical trial

   Relevance:

   demonstrated efficacy comparable to pentamidine. METHODS: This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage T

2. Spectrum-malaria: a user-friendly projection tool for health impact assessment and strategic planning by malaria control programmes in sub-Saharan... (Publications)

   Spectrum-malaria: a user-friendly projection tool for health impact assessment and strategic planning by malaria control programmes in sub-Saharan Africa

   Relevance:

   fitted to proportional burden reductions simulated in the P. falciparum dynamic transmission model OpenMalaria. RESULTS: In projections for Nigeria, ITNs, IRS, CMU, and CMS scale-up reduced health burdens

3. KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes (Publications)

   KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes

   Relevance:

   bioinformatics expertise to scan and analyze raw sequencing data in a matter of minutes. KvarQ is open-source, and pre-compiled packages with a graphical user interface are available at http://www.swisstph

4. Repeated mass distributions and continuous distribution of long-lasting insecticidal nets: modelling sustainability of health benefits from mosquito... (Publications)

   Repeated mass distributions and continuous distribution of long-lasting insecticidal nets: modelling sustainability of health benefits from mosquito nets, depending on case management

   Relevance:

   were also examined. METHODS: Dynamic simulations of malaria in humans and mosquitoes were run on the OpenMalaria platform, using stochastic individual-based simulation models. LLINs were distributed in a

5. Prices and mark-ups on antimalarials: evidence from nationally representative studies in six malaria-endemic countries (Publications)

   Prices and mark-ups on antimalarials: evidence from nationally representative studies in six malaria-endemic countries

   Relevance:

   Benin where wholesaler and retailer mark-ups are regulated; however, unlicensed drug vendors based in open-air markets did not adhere to the pricing regime. These findings indicate that mark-ups on antimalarials

6. Malaria and its possible control on the island of Príncipe (Publications)

   Malaria and its possible control on the island of Príncipe

   Relevance:

   under mosquito nets and were at reduced risk of infection. Conversely, people living in houses with openings between the top of the wall and the roof had higher risk of infection. CONCLUSION: This high incidence

7. Priority setting in HIV, tuberculosis, and malaria - new cost-effectiveness results from WHO-CHOICE (Publications)

   Priority setting in HIV, tuberculosis, and malaria - new cost-effectiveness results from WHO-CHOICE

   Relevance:

   determine the cost-effectiveness of the selected interventions. Impact modelling was performed using the OpenMalaria platform for malaria and using the Goals and TIME (TB Impact Model and Estimates) models in

8. Effectiveness of Nifurtimox Eflornithine Combination Therapy (NECT) in <em>T. b. gambiense</em> second stage sleeping sickness patients in the... (Publications)

   Effectiveness of Nifurtimox Eflornithine Combination Therapy (NECT) in <em>T. b. gambiense</em> second stage sleeping sickness patients in the Democratic Republic of Congo: report from a field study

   Relevance:

   ess results after the 24-month follow-up visit. METHODOLOGY/PRINCIPAL FINDINGS: In a multicenter, open label, single arm phase IIIb study, second stage gambiense HAT patients were treated with NECT in

9. Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with <em>Trichuris... (Publications)

   Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with <em>Trichuris trichiura</em>: a randomized controlled trial protocol

   Relevance:

   540 T. trichiura-infected adolescents aged 12-19 years on Pemba Island (Tanzania). The trial will be open-label with blinded outcome assessors. The primary objective is to demonstrate non-inferiority of orally

10. Health technology assessment in high, middle, and low-income countries: new systematic and interdisciplinary approach for sound informed-policy... (Publications)

    Health technology assessment in high, middle, and low-income countries: new systematic and interdisciplinary approach for sound informed-policy making: research protocole

    Relevance:

    for the seven countries, but also for the global, regional, and national endeavors with regards to opening a room for HTA best application and optimization. It will reveal lessons learned, determine gaps