Egg-laying and locomotory screens with <em>C. elegans </em>yield a nematode-selective small molecule stimulator of neurotransmitter release (Publications)
Nematode parasites of humans, livestock and crops dramatically impact human health and welfare. Alarmingly, parasitic nematodes of animals have rapidly evolved resistance to anthelmintic drugs, and tr
<em>Mycobacterium tuberculosis</em> genetic diversity and drug resistance conferring mutations in the Democratic Republic of the Congo (Publications)
Background: The Democratic Republic of the Congo (DRC) belongs to the 22 tuberculosis (TB) high-burden countries and to the 27 high-burden multidrug-resistant (MDR)-TB countries. To date, there are no
Benzyl- and dibenzyl tetrahydropyridinylidene ammonium salts with antiplasmodial and antitrypanosomal activity (Publications)
Several 1-benzyl and 1,3-dibenzyl derivatives of tetrahydropyridinylidene salts with differing electron withdrawing substituents at the aromatic residues have been prepared. In addition, the amine moi