Comparing land use regression and dispersion modelling to assess residential exposure to ambient air pollution for epidemiological studies (Publications)
addresses of participants in 13 cohorts for NO2; 7 for PM10 and 4 for PM2.5. Additionally, we compared the DM estimates with measured concentrations at the 20-40 ESCAPE monitoring sites in each area. RESULTS: [...] annual average concentrations of NO2, PM10 and PM2.5 were 0.75 (0.19-0.89), 0.39 (0.23-0.66) and 0.29 (0.22-0.81) for 112,971 (13 study areas), 69,591 (7) and 28,519 (4) addresses respectively. The median [...] NO2; 0.58 (0.36-0.88) for PM10 and 0.58 (0.39-0.66) for PM2.5....
Comparing land use regression and dispersion modelling to assess residential exposure to ambient air pollution for epidemiological studies (Publications)
addresses of participants in 13 cohorts for NO2; 7 for PM10 and 4 for PM2.5. Additionally, we compared the DM estimates with measured concentrations at the 20-40 ESCAPE monitoring sites in each area. RESULTS: [...] annual average concentrations of NO2, PM10 and PM2.5 were 0.75 (0.19-0.89), 0.39 (0.23-0.66) and 0.29 (0.22-0.81) for 112,971 (13 study areas), 69,591 (7) and 28,519 (4) addresses respectively. The median [...] NO2; 0.58 (0.36-0.88) for PM10 and 0.58 (0.39-0.66) for PM2.5....
Mortality from neurodegenerative disease and exposure to extremely low-frequency magnetic fields: 31 years of observations on Swiss railway employees (Publications)
Alzheimer's disease. For every 10 microT years of cumulative exposure senile dementia mortality increased by 5.7% (95% CI = 1.3-10.4), Alzheimer's disease by 9.4% (95% CI = 2.7-16.4) and amyotrophic lateral [...] from several neurodegenerative conditions in Swiss railway employees. METHODS: We studied a cohort of 20,141 Swiss railway employees with 464,129 person-years of follow-up between 1972 and 2002. For each
Mortality from neurodegenerative disease and exposure to extremely low-frequency magnetic fields: 31 years of observations on Swiss railway employees (Publications)
Alzheimer's disease. For every 10 microT years of cumulative exposure senile dementia mortality increased by 5.7% (95% CI = 1.3-10.4), Alzheimer's disease by 9.4% (95% CI = 2.7-16.4) and amyotrophic lateral [...] from several neurodegenerative conditions in Swiss railway employees. METHODS: We studied a cohort of 20,141 Swiss railway employees with 464,129 person-years of follow-up between 1972 and 2002. For each
Incidence and risk factors of surgical site infections and related antibiotic resistance in Freetown, Sierra Leone: a prospective cohort study (Publications)
riaceae, 9 (18.4%) were Non-fermenting gram-negative bacilli and 10 (12.2%) were Enterococci. The most common isolates were Escherichia coli (12, 24.5%), Klebsiella pneumoniae (10, 20.4%), Acinetobacter [...] er baumannii (5, 10.2%), Klebsiella oxytoca (4, 8.2%) and Enterococcus faecalis (4, 8.2%). The Enterobacteriaceae were either resistance to carbapenems (4, 8.2%) or were extended-spectrum beta-lactamase [...] contaminated 17 (43.6%) than in clean-contaminated 12 (30.8%) and clean 10 (25.6%)...
Incidence and risk factors of surgical site infections and related antibiotic resistance in Freetown, Sierra Leone: a prospective cohort study (Publications)
riaceae, 9 (18.4%) were Non-fermenting gram-negative bacilli and 10 (12.2%) were Enterococci. The most common isolates were Escherichia coli (12, 24.5%), Klebsiella pneumoniae (10, 20.4%), Acinetobacter [...] er baumannii (5, 10.2%), Klebsiella oxytoca (4, 8.2%) and Enterococcus faecalis (4, 8.2%). The Enterobacteriaceae were either resistance to carbapenems (4, 8.2%) or were extended-spectrum beta-lactamase [...] contaminated 17 (43.6%) than in clean-contaminated 12 (30.8%) and clean 10 (25.6%)...
Inhibitory activity of marine sponge-derived natural products against parasitic protozoa (Publications)
furospongin-1 (3), furospongin-4 (4), and demethylfurospongin-4 (5); four linear meroterpenes: 2-(hexaprenylmethyl)-2-methylchromenol (6), 4-hydroxy-3-octaprenylbenzoic acid (7), 4-hydroxy-3-tetraprenylphenylacetic [...] cruzi, with IC50 values around 4 mu g/mL. Compound 12 showed the strongest leishmanicidal activity (IC50 0.75 mu g/mL), which was comparable to that of miltefosine (IC50 0.20 mu g/mL). The best antiplasmodial [...] ylacetic acid (8), and heptaprenyl-p-quinol (9); a linear...
Inhibitory activity of marine sponge-derived natural products against parasitic protozoa (Publications)
furospongin-1 (3), furospongin-4 (4), and demethylfurospongin-4 (5); four linear meroterpenes: 2-(hexaprenylmethyl)-2-methylchromenol (6), 4-hydroxy-3-octaprenylbenzoic acid (7), 4-hydroxy-3-tetraprenylphenylacetic [...] cruzi, with IC50 values around 4 mu g/mL. Compound 12 showed the strongest leishmanicidal activity (IC50 0.75 mu g/mL), which was comparable to that of miltefosine (IC50 0.20 mu g/mL). The best antiplasmodial [...] ylacetic acid (8), and heptaprenyl-p-quinol (9); a linear...
Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents (Publications)
activity in the trypanosomal STIB900 mouse model giving 3/4 or 4/4 cures at dosage of 20 mg/kg i.p. and three showed similar efficacy at dosage of 10 mg/kg or lower
Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents (Publications)
activity in the trypanosomal STIB900 mouse model giving 3/4 or 4/4 cures at dosage of 20 mg/kg i.p. and three showed similar efficacy at dosage of 10 mg/kg or lower