Non-Hodgkin lymphoma incidence in the Swiss HIV Cohort Study before and after highly active antiretroviral therapy (Publications)
05-0.25) 7 to10 years afterwards. CONCLUSIONS: HAART greatly reduced the incidence of NHL in PHIV, and the influence of CD4 cell count on NHL risk. The beneficial effect remained strong up to 10 years after [...] HAART use was associated with a decline in NHL incidence [HR = 0.26; 95% confidence interval (CI), 0.20-0.33], and this decline was greater for primary brain lymphomas than other NHL. Among non-HAART users [...] users, being a man having sex with men, being 35 years of age or older, or,...
Revised EU and WHO air quality thresholds: where does Europe stand? (Publications)
and at 29.6 (21.9, 37.0%) above the EU values, whereas for NO2, the estimates were at 67.4% (57.9, 75.8%) and 20.2% (13.3, 28.5%), respectively. Our high-resolution model-based predictions are readily available [...] to levels above the new suggested thresholds for the three most harmful pollutants, namely PM2.5, PM10, and NO2. The results have shown that in 2021, 97.6% (95% credible interval: 95.1, 99.2%) of the total [...] values, while 47.5% (36.2, 59.5%) lived in areas where the revised EU...
Revised EU and WHO air quality thresholds: where does Europe stand? (Publications)
and at 29.6 (21.9, 37.0%) above the EU values, whereas for NO2, the estimates were at 67.4% (57.9, 75.8%) and 20.2% (13.3, 28.5%), respectively. Our high-resolution model-based predictions are readily available [...] to levels above the new suggested thresholds for the three most harmful pollutants, namely PM2.5, PM10, and NO2. The results have shown that in 2021, 97.6% (95% credible interval: 95.1, 99.2%) of the total [...] values, while 47.5% (36.2, 59.5%) lived in areas where the revised EU...
Antiprotozoal diterpenes from <em>Perovskia abrotanoides</em> (Publications)
and one isopimarane-type derivatives. Among these, (5R,10S)-11-hydroxy-12-methoxy-20-norabieta-8,11,13-triene (2: ), 12-hydroxy-norabieta-1(10),8,11,13-tetraene-1,11-furan (6: ), and 12-methoxybarbatusol [...] (8: ) with an IC50 of 2.9 microM (SI 19.2) against P. falciparum, and miltiodiol (10: ) with an IC50 of 0.5 microM (SI 10.5) against T. b. rhodesiense. None of the compounds exhibited selective toxicity [...] comparison to cytotoxicity on rat myoblast (L6) cells. Particularly active were...
Antiprotozoal diterpenes from <em>Perovskia abrotanoides</em> (Publications)
and one isopimarane-type derivatives. Among these, (5R,10S)-11-hydroxy-12-methoxy-20-norabieta-8,11,13-triene (2: ), 12-hydroxy-norabieta-1(10),8,11,13-tetraene-1,11-furan (6: ), and 12-methoxybarbatusol [...] (8: ) with an IC50 of 2.9 microM (SI 19.2) against P. falciparum, and miltiodiol (10: ) with an IC50 of 0.5 microM (SI 10.5) against T. b. rhodesiense. None of the compounds exhibited selective toxicity [...] comparison to cytotoxicity on rat myoblast (L6) cells. Particularly active were...
Long-term exposure to air pollution and mortality in a Danish nationwide administrative cohort study: beyond mortality from cardiopulmonary disease... (Publications)
people died from natural causes. Long-term exposure to PM2.5 (mean: 12.4 microg/m(3)), NO2 (20.3 microg/m(3)), and/or BC (1.0 x 10(-5)/m) was statistically significantly associated with all studied mortality [...] cancer (1.19; 1.15-1.24), diabetes (1.10; 1.04-1.16), dementia (1.05; 1.00-1.10), psychiatric disorders (1.38; 1.27-1.50), asthma (1.13; 0.94-1.36), and ALRI (1.14; 1.09-1.20). Associations with long-term exposure
Long-term exposure to air pollution and mortality in a Danish nationwide administrative cohort study: beyond mortality from cardiopulmonary disease... (Publications)
people died from natural causes. Long-term exposure to PM2.5 (mean: 12.4 microg/m(3)), NO2 (20.3 microg/m(3)), and/or BC (1.0 x 10(-5)/m) was statistically significantly associated with all studied mortality [...] cancer (1.19; 1.15-1.24), diabetes (1.10; 1.04-1.16), dementia (1.05; 1.00-1.10), psychiatric disorders (1.38; 1.27-1.50), asthma (1.13; 0.94-1.36), and ALRI (1.14; 1.09-1.20). Associations with long-term exposure
Low prevalence of bovine tuberculosis in Somali pastoral livestock, southeast Ethiopia (Publications)
using a xtgee model for each species. The individual animal prevalence was 2.0% [95% confidence interval (CI), 0.5-8.4], 0.4% (95% CI, 0.1-3%), and 0.2% (95% CI, 0.03-1.3) in cattle, camels, and goats [...] derivative (PPD) reactors in cattle, camels, and goats was 0.7% (95% CI, 0.2-2.0%), 10.0% (95% CI, 7.0-14.0%), and 1.9 (95% CI, 0.9-4.0%), respectively, whereby camels had an odds ratio of 16.5 (95% CI, 5.0-55
Low prevalence of bovine tuberculosis in Somali pastoral livestock, southeast Ethiopia (Publications)
using a xtgee model for each species. The individual animal prevalence was 2.0% [95% confidence interval (CI), 0.5-8.4], 0.4% (95% CI, 0.1-3%), and 0.2% (95% CI, 0.03-1.3) in cattle, camels, and goats [...] derivative (PPD) reactors in cattle, camels, and goats was 0.7% (95% CI, 0.2-2.0%), 10.0% (95% CI, 7.0-14.0%), and 1.9 (95% CI, 0.9-4.0%), respectively, whereby camels had an odds ratio of 16.5 (95% CI, 5.0-55
Cost-effectiveness of the introduction of a pre-erythrocytic malaria vaccine into the expanded program on immunization in Sub-Saharan Africa: analysis... (Publications)
n was simulated in populations of 100,000 people at 10 different entomological inoculation rates (EIRs), using an existing stochastic model and a 10-year time horizon. Incremental cost-effectiveness ratios [...] life-year averted, 52.4% of parameterizations predicted cost-effectiveness in the primary analysis. CONCLUSIONS: Cost-effectiveness of RTS,S will be maximal in low endemicity settings (EIR 2-20 ibpa). Widespread [...] always substantially exceeded case management savings. Optimal...
