Seasonal drivers and risks of aquatic pesticide pollution in drought and post-drought conditions in three Mediterranean watersheds (Publications)
South Africa has a Mediterranean climate, which has in part led to an abundance of agriculturally productive land supporting the wheat, deciduous fruit, wine, and citrus industries. South Africa is the [...] the leading pesticide user in Sub-Saharan Africa. There is limited data on the pesticide pollution of surface water over different seasons in low- and middle-income countries. We evaluated the seasonal drivers
Seasonal drivers and risks of aquatic pesticide pollution in drought and post-drought conditions in three Mediterranean watersheds (Publications)
South Africa has a Mediterranean climate, which has in part led to an abundance of agriculturally productive land supporting the wheat, deciduous fruit, wine, and citrus industries. South Africa is the [...] the leading pesticide user in Sub-Saharan Africa. There is limited data on the pesticide pollution of surface water over different seasons in low- and middle-income countries. We evaluated the seasonal drivers
Professional activities at Swiss TPH Professor Christian Lengeler leads the Malaria Interventions Group in the Epidemiology and Public Health department at Swiss TPH, and is Professor of Epidemiology at [...] and was responsible for pioneering many developments in large-scale vector control in sub-Saharan Africa. Since 1999, he has been supporting implementation of the National Malaria Control Programme in DR
Repositioning of a diaminothiazole series confirmed to target the cyclin-dependent kinase CRK12 for use in the treatment of African animal... (Publications)
congolense and Trypanosoma vivax, is a major problem in cattle and other livestocks in sub-Saharan Africa. Current treatments are threatened by the emergence of drug resistance and there is an urgent need [...] A medicinal chemistry program, focused on deriving more soluble analogues, led to development of a lead compound capable of curing cattle infected with both T. congolense and T. vivax via intravenous dosing
Buruli ulcer disease: prospects for a vaccine (Publications)
mutilating disease leading to severe disability; it is the third most common mycobacterial infection in immunocompetent people after tuberculosis and leprosy. It is most endemic in West Africa, but cases have
Repositioning of a diaminothiazole series confirmed to target the cyclin-dependent kinase CRK12 for use in the treatment of African animal... (Publications)
congolense and Trypanosoma vivax, is a major problem in cattle and other livestocks in sub-Saharan Africa. Current treatments are threatened by the emergence of drug resistance and there is an urgent need [...] A medicinal chemistry program, focused on deriving more soluble analogues, led to development of a lead compound capable of curing cattle infected with both T. congolense and T. vivax via intravenous dosing
Buruli ulcer disease: prospects for a vaccine (Publications)
mutilating disease leading to severe disability; it is the third most common mycobacterial infection in immunocompetent people after tuberculosis and leprosy. It is most endemic in West Africa, but cases have
vector-borne diseases in Africa. Parasit Vectors . 2025;18:45. DOI: 10.1186/s13071-024-06621-x Swai J.K, Moore S.J. Beyond repellents: spatial emanators for the control of malaria in Africa. Lancet . 2025;40 [...] evaluated new types of indoor residual spray (IRS), insecticide treated nets (ITNs) insecticide treated house screening, topical repellents (TR), odour baited traps, volatile pyrethroid spatial repellents (VPSR) [...] cal effects of differentially treated ITNs in a multi-site...
evolved into scientific hot spots in Africa under his leadership. Marcel Tanner believes that in order to secure a sustainable future, the countries of sub-Saharan Africa need not only development funding [...] TPH to Jürg Utzinger. During his 18 years in office, the institute evolved to become one of the leading points of contact for global health issues. Directorate A Tireless Leader Marcel Tanner in Ifakara [...] and continue the fight against diseases of poverty such as malaria, tuberculosis...
<em>In vitro</em> screening of traditional South African malaria remedies against <em>Trypanosoma brucei rhodesiense</em>, <em>Trypanosoma cruzi,... (Publications)
Three hundred extracts were prepared from plants traditionally used in South Africa to treat malaria and screened IN VITRO for activity against TRYPANOSOMA BRUCEI RHODESIENSE, TRYPANOSOMA CRUZI, LEISHMANIA [...] This screening is the starting point for a HPLC-based activity profiling project in antiprotozoal lead discovery
