School-based preventive chemotherapy program for schistosomiasis and soil-transmitted helminth control in Angola: 6-year impact assessment (Publications)
0% (95%CI -48.6, 20.6). Prevalence of any STH in Huambo was 16.3%, Uige 65.1%, and Zaire 28.2%. Relative reduction in STH prevalence for Huambo was -28.4% (95%CI -92.1, 35.2), Uige -10.7% (95%CI -30.2, [...] asis and STH surveys, respectively. Prevalence of any schistosomiasis in Huambo was 29.6%, Uige 35.4%, and Zaire 28.2%. Relative reduction in schistosomiasis prevalence from 2014 for Huambo was 18.8% (95% [...] 8.8), and Zaire -20.9% (95%CI -79.5, 37.8). A higher proportion of...
Association between short term exposure to fine particulate matter and heart rate variability in older subjects with and without heart disease (Publications)
daily 20 minute measures of HRV (including a paced breathing protocol) were made in the homes of 34 elderly individuals with (n = 21) and without (n = 13) cardiovascular disease (CVD) over a 10 day period [...] temperature, mean heart rate, and medication use did not find a significant association between a 10 microg/m3 increase in 1 hour mean outdoor PM2.5 before the HRV measurement and a change in HF-HRV power [...] CVD (5% decrease in median HF-HRV (95% CI -34 to 36)). Similarly, no...
Air pollution from road traffic and systemic inflammation in adults: a cross-sectional analysis in the European ESCAPE project (Publications)
systemic inflammation. However, cohort participants living on a busy (> 10,000 vehicles/day) road had elevated CRP values (10.2%, 95% CI 2.4-18.8%, compared to persons living in a quiet residential street with [...] Annual NOx concentration was also positively associated with levels of CRP (3.2%, 95% CI 0.3-6.1 per 20 microg/m3), but the effect estimate was more sensitive to model adjustments. For fibrinogen, no consistent
Association between short term exposure to fine particulate matter and heart rate variability in older subjects with and without heart disease (Publications)
daily 20 minute measures of HRV (including a paced breathing protocol) were made in the homes of 34 elderly individuals with (n = 21) and without (n = 13) cardiovascular disease (CVD) over a 10 day period [...] temperature, mean heart rate, and medication use did not find a significant association between a 10 microg/m3 increase in 1 hour mean outdoor PM2.5 before the HRV measurement and a change in HF-HRV power [...] CVD (5% decrease in median HF-HRV (95% CI -34 to 36)). Similarly, no...
Air pollution from road traffic and systemic inflammation in adults: a cross-sectional analysis in the European ESCAPE project (Publications)
systemic inflammation. However, cohort participants living on a busy (> 10,000 vehicles/day) road had elevated CRP values (10.2%, 95% CI 2.4-18.8%, compared to persons living in a quiet residential street with [...] Annual NOx concentration was also positively associated with levels of CRP (3.2%, 95% CI 0.3-6.1 per 20 microg/m3), but the effect estimate was more sensitive to model adjustments. For fibrinogen, no consistent
Long-term exposure to traffic-related air pollution and stroke: a systematic review and meta-analysis (Publications)
96–1.23) per 10 μg/m3 PM10, 1.08 (0.89–1.32) per 5 μg/m3 PM2.5, 0.98 (0.92; 1.05) per 10 μg/m3 NO2 and 0.99 (0.94; 1.04) per 20 μg/m3 NOx with little to moderate heterogeneity based on 6, 5, 4, 7 and 8 studies
Long-term exposure to traffic-related air pollution and stroke: a systematic review and meta-analysis (Publications)
96–1.23) per 10 μg/m3 PM10, 1.08 (0.89–1.32) per 5 μg/m3 PM2.5, 0.98 (0.92; 1.05) per 10 μg/m3 NO2 and 0.99 (0.94; 1.04) per 20 μg/m3 NOx with little to moderate heterogeneity based on 6, 5, 4, 7 and 8 studies
Drugs for treating urinary schistosomiasis (Publications)
Mild to moderate adverse events were recorded in two trials. A comparison of metrifonate (10 mg/kg x 3, once every 4 months for one year) with praziquantel (standard dose) showed little difference in par [...] l failure. For praziquantel, there was no significant difference in effect between 20 mg/kg x 2, 30 mg/kg x 1, and 20 mg/kg x 1, and the standard dose for all outcomes. One small trial of artesunate showed [...] were reported (1 trial). One metrifonate dose was inferior to three doses...
Drugs for treating urinary schistosomiasis (Publications)
Mild to moderate adverse events were recorded in two trials. A comparison of metrifonate (10 mg/kg x 3, once every 4 months for one year) with praziquantel (standard dose) showed little difference in par [...] l failure. For praziquantel, there was no significant difference in effect between 20 mg/kg x 2, 30 mg/kg x 1, and 20 mg/kg x 1, and the standard dose for all outcomes. One small trial of artesunate showed [...] were reported (1 trial). One metrifonate dose was inferior to three doses...
Prevalence and force of <em>Plasmodium vivax</em> blood-stage infection and associated clinical malaria burden in the Brazilian Amazon (Publications)
ratio (aHR) 2.6 (1.9-5.7)] and clinical disease [aHR 10.6 (2.4-47.2)]. P. falciparum infection was associated with previous malarial episodes [HR 9.7 (4.5-20.9)]. Subjects who reported possession of a bed net [...] net [incidence rate ratio (IRR) 1.6 (1.2-2.2)] or previous malaria episodes [IRR 3.0 (2.0-4.5)] were found to have significantly higher P. vivax molFOB. MAIN CONCLUSIONS: Overall, P. vivax infection prevailed
